Atividade Investigacional/Científica

Novembro 14, 2022

Atividade Investigacional/Científica

O Serviço de Reumatologia desenvolve uma atividade intensa de investigação em diversas áreas da Reumatologia em colaboração estreita com a Unidade de Investigação em Reumatologia do Instituto de Medicina Molecular da Faculdade de Medicina da Universidade de Lisboa.

Relatório de Atividades – 2024

Projetos a decorrer no Serviço de Reumatologia/Unidade de Investigação em Reumatologia

Estudo Prognóstico da Arterite Temporal / PROgnosis of TEmporal Arteritis Study (PROTEA)
Is ultrasound a good surrogate marker for remission in RA? (Association of ultrasound and histological synovitis in rheumatoid arthritis patients in clinical remission).
Blood biomarkers of synovial tissue phenotype as predictors of response to TNF inhibitors and tocilizumab in rheumatoid arthritis
IL-6-blockade in rheumatoid arthritis patients: impact on Tfh subsets and its relation to treatment response
Avaliação Eficácia e Segurança Zoledronato a longo Prazo na Doença Óssea de Paget
Evaluation of celastrol as a candidate for the treatment of rheumatoid arthritis
B cells in Juvenile Idiopathic Arthritis
Síndromes autoinflamatórios – análise nacional com base na Reuma.pt
Ensaio clínico de mesoterapia
Outcomes na idade adulta da Artrite Idiopática Juvenil
Avaliação clínica, analítica, radiológica e ecográfica de doentes com artrite em fase inicial
Loss of follow up dos doentes sob Biológicos
The role of lncRNAs in Rheumatoid Arthritis-associated bone degradation
Serum sphingolipids as candidate biomarkers in Rheumatoid Arthritis
Systemic Sclerosis Clinical Study (SSPECT)
Predictors of response to ultrasound-guided sacroiliac joint corticosteroid-injection in patients with active sacroiliitis
Paget’s disease of bone (PDB) – Contribution to the study of its pathogenesis
Clinical Outcomes of African Patients drom Portuguese Speaking Countries Evacuated for Medical Assessment in Portugal– Rheumatology as a case study
Protocolo de Actuação na Nefropatia Lúpica
Predictors of radiographic progression in Psoriatic Arthritis patients
Tapering biologics in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
Long term effect of tofacitinib on bone: friend or foe?

Informação atualizada em Agosto de 2021

Abaixo encontram-se listadas as publições dos últimos 5 anos:

2012

Canhão H, Rodrigues AM, Mourão AF, Martins F, Santos MJ, Canas-Silva J, Polido-Pereira J, Pereira Silva JA, Costa JA, Araújo D, Silva C, Santos H, Duarte C, da Silva JA, Pimentel-Santos FM, Branco JC, Karlson EW, Fonseca JE, Solomon DH. (2012) Comparative effectiveness and predictors of response to tumor necrosis factor inhibitor therapies in rheumatoid arthritis. Rheumatology (Oxford) 51:2020-6

Cascão R, Vidal B, Raquel H, Neves-Costa A, Figueiredo N, Gupta V, Fonseca JE, Moita LF. (2012) Effective treatment of rat adjuvant-induced arthritis by celastrol. Autoimmun Rev. 11:856-62

Navalho M, Resende C, Rodrigues AM, Ramos F, Gaspar A, Silva JA, Fonseca JE, Campos J, Canhão H.(2012) Bilateral MR Imaging of the Hand and Wrist in Early and Very-Early Inflammatory Arthritis: Tenosynovitis Is Associated with Progression to Rheumatoid Arthritis. Radiology. 264:823-33

Polido-Pereira J, Rodrigues AM, Canhão H, Saraiva F, da Silva JA, Fonseca JE. (2012) Primary biliary cirrhosis in a rheumatoid arthritis patient treated with rituximab, a case-based review. Clin Rheumatol. 31:385-9 (

Cascão R, Polido-Pereira J, Canhão H, Rodrigues AM, Navalho M, Raquel H, Mourão AF, Resende C , Fonseca JE, Moita LF (2012) Caspase-1 is active since the early phase of Rheumatoid Arthritis. Clin Exp Rheumatol. 30:144

Pimentel-Santos FM, Ligeiro D, Matos M, Mourão AF, de Sousa EV, Pinto P, Ribeiro A, Santos H, Barcelos A, Godinho F, Cruz M, Fonseca JE, Guedes-Pinto H, Trindade H, Brown MA, Branco JC (2012) ANKH and Susceptibility to and Severity of Ankylosing Spondylitis. J Rheumatol. 39:131-4 .

Santos MJ, Carmona-Fernandes D, Canhão H, Canas da Silva J, Fonseca JE, Gil V. (2012) Early Vascular Alterations in SLE and RA Patients-A Step towards Understanding the Associated Cardiovascular Risk. PLoS One. 7:e44668 .

Alonso-Perez E, Suarez-Gestal M, Calaza M, Ordi-Ros J, Balada E, Bijl M, Papasteriades C, Carreira P, Skopouli FN, Witte T, Endreffy E, Marchini M, Migliaresi S, Sebastiani GD, Santos MJ, Suarez A, Blanco FJ, Barizzone N, Ruzickova S, Lauwerys BR, Gomez-Reino JJ, Gonzalez A. (2012) Further evidence of subphenotype association with Systemic Lupus Erythematosus susceptibility loci: a case-only study. Plos One 7: e45356.

Alonso-Perez E, Suarez-Gestal M, Calaza M, Sebastiani GD, Pullmann R, Papasteriades C, Kovacs A, Skopouli FN, Bijl M, Suarez A, Marchini M, Migliaresi S, Carreira P, Ordi-Ros J, Witte T, Ruzickova S, Santos MJ, Barizzone N, Blanco FJ, Lauwerys BR, Gomez-Reino JJ, Gonzalez A, European Consortium of SLE DNA Collections. (2012) Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study. Arthritis Res Ther. Apr 27, 14(2):R94.

Moura RA, Graca L, Fonseca JE. (2012) To B or Not to B the Conductor of Rheumatoid Arthritis Orchestra. Clin Rev Allergy Immunol. 43:281-91

Madruga Dias J, Costa MM, Romeu JC, Soares-Almeida L, Filipe P, Pereira da Silva JA. (2012) Pachydermodactyly in a 16-year-old adolescent boy. J Clin Rheumatol. 18:246-8.

Madruga Dias J, Costa MM, Pereira da Silva JA, Viana de Queiroz M. (2012) Parry-Romberg syndrome in an 11-year-old female with neurological manifestations without brain imaging abnormalities. Joint Bone Spine 79:419-21.

Pimentel-Santos FM, Mourão AF, Ribeiro C, Costa J, Santos H, Barcelos A, Pinto P, Godinho F, Cruz M, Vieira-Sousa E, Santos RA, Rabiais S, Félix J, Fonseca JE, Guedes-Pinto H, Brown MA, Branco JC, CORPOREA Study Group (2012) Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts. Clin Rheumatol 31:447-54.

Rodrigues AM, Caetano-Lopes J, Vale AC, Vidal B, Lopes A, Aleixo I, Polido-Pereira J, Sepriano A, Perpétuo IP, Monteiro J, Vaz MF, Fonseca JE, Canhão H. (2012) Low osteocalcin/collagen type I bone gene expression ratio is associated with hip fragility fractures. Bone 51:981-9

Rodrigues AM, Caetano-Lopes J, Vale AC, Aleixo I, Pena AS, Faustino A, Sepriano A, Polido-Pereira J, Vieira-Sousa E, Lucas R, Romeu JC, Monteiro J, Vaz MF, Fonseca JE, Canhão H. (2012) Smoking is a predictor of worse trabecular mechanical performance in hip fragility fracture patients. J Bone Miner Metab 30:692-9.

Santos MJ, Canhão H, Conde M, Fonseca JE, Mourão AF, Ramos F, Costa L, Ramos MP, Cabral M, Estanqueiro P, Melo-Gomes S, Salgado M, Melo-Gomes J. (2012) Portuguese recommendations for the use of biological therapies in children and adolescents with juvenile idiopathic arthritis – December 2011 update. Acta Reumatol Port. 37:48-68.

Machado P, Bernardo A, Rodrigues A, Malcata A, Nour D, Vieira-Sousa E, Godinho F, Pimentel F, Canhão H, Santos H, Cunha I, Fonseca JE, Costa J, Costa L, Cunha-Miranda L, Maurício L, Cruz M, Santos MJ, Bernardes M, Bogas M, Valente P, Ramiro S, Barcelos A. (2012) Portuguese recommendations for the use of biological therapies in patients with axial spondyloarthritis – December 2011 update. Acta Reumatol Port. 37:40-7.

Machado P, Bogas M, Ribeiro A, Costa J, Neto A, Sepriano A, Raposo A, Cravo AR, Vilar A, Furtado C, Ambrósio C, Miguel C, Vaz C, Catita C, Nour D, Araújo D, Vieira-Sousa E, Teixeira F, Brandão F, Canhão H, Cordeiro I, Gonçalves I, Ferreira J, Fonseca JE, Silva JA, Romeu J, Ferreira J, Costa L, Maurício L, Cunha-Miranda L, Parente M, Coutinho M, Cruz M, Oliveira M, Salvador MJ, Santos MJ, Pinto P, Valente P, Abreu P, Roque R, Ramiro S, Capela S, Las V, Barcelos A. (2012) 2011 Portuguese recommendations for the use of biological therapies in patients with psoriatic arthritis. Acta Reumatol Port. 37:26-39.

Laires PA, Canhão H, Araújo D, Fonseca JE, Machado P, Mourão AF, Ramiro S, Romeu JC, Santos MJ, Silva I, Silva JA, Sousa E, Tavares V, Gouveia N, Branco JC.(2012) CoReumaPt Protocol: The Portuguese Cohort of Rheumatic Diseases. Acta Reumatol Port. 37:18-24.

Machado P, Santos MJ, Fonseca JE. Recommendations of the Portuguese Society of Rheumatology: a contribution towards improving the quality of health care. Acta Reumatol Port. 37:7-8.

Silva I, Mourão AF, Ramiro S, Rodrigues A, Miguel C, Sampaio L, Faustino A, Vaz C, Canhão H, Cruz M, Neto A, Cravo AR, Ribeiro A, Brandão A, Peixoto D, Medeiros D, Santos FA, Teixeira F, Gonçalves I, Silva JP, Gomes JM, Maurício L, Simões E, Salvador MJ, Silva M, Nero P, Roque R, Barros R, André R, Falcão S, Serra S, Tavares V, Branco JC. (2012) Recomendações portuguesas para o tratamento e controlo farmacológico da dor nas artropatias inflamatórias. Acta Reumatol Port. 37:160-174.

Roque R, Vinagre F, Gonçalves P, Santos MJ, Canas da Silva J (2012) Manifestações reumáticas da Sífilis Secundária. Acta Reumatol Port. 37:175-9.

Vidal B, Pinto A, Galvão MJ, Santos AR, Rodrigues A, Cascão R, Abdulghani S, Caetano-Lopes J, Ferreira A, Fonseca JE, Canhao H. Bone histomorphometry revisited. Acta Reumatol Port. 37:294-300.

Duarte R, Campainha S, Cotter J, Rosa B, Varela P, Correia A, Canhão H, Fonseca JE. Position paper on tuberculosis screening in patients with immune mediated inflammatory diseases 253 candidates for biological therapy. Acta Reumatol Port. 37:253-259.

2013

Madruga Dias J, Costa MM, Dias S, Almeida A. (2013) Osteomesopyknosis: An incidental discovery due to back pain. Joint Bone Spine 80: 223-4.

Costa N, Pires AE, Gabriel AM, Goulart LF, Pereira C, Leal B, Queiros AC, Chaara W, Moraes-Fontes MF, Vasconcelos C, Ferreira C, Martins J, Bastos M, Santos MJ, Pereira MA, Martins B, Lima M, João C, Six A, Demengeot J, Fesel C. (2013) Broadened T-cell repertoire diversity in ivIg-treated SLE patients is also related to the individual status of regulatory T-cells. J Clin Immunol 33. 349-60

Laires PA, Exposto F, Mesquita R, Martins AP, Cunha-Miranda L, Fonseca JE.(2013) Patients’ access to biologics in rheumatoid arthritis: a comparison between Portugal and other European countries. Eur J Health Econ 14: 875-85.

Carmona-Fernandes D, Santos MJ, Canhão H, Fonseca JE.(2013) Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile. BMC Med. 4,11:98. (

Cui J Stahl EA Saevarsdottir S Miceli C Diogo D Trynka G Raj T Mirkov MU Canhao H Ikari K Terao C Okada Y Wedrén S Askling J Yamanaka H Momohara S Taniguchi A Ohmura K Matsuda F Mimori T Gupta N Kuchroo M Morgan AW Isaacs JD Wilson AG Hyrich KL Herenius M Doorenspleet ME Tak PP Crusius JB van der Horst-Bruinsma IE Wolbink GJ van Riel PL van de Laar M Guchelaar HJ Shadick NA Allaart CF Huizinga TW Toes RE Kimberly RP Bridges SL Jr Criswell LA Moreland LW Fonseca JE de Vries N Stranger BE De Jager PL Raychaudhuri S Weinblatt ME Gregersen PK Mariette X Barton A Padyukov L Coenen MJ Karlson EW Plenge RM. (2013) Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis. PLoS Genet. 9(3):e1003394.

Romão VC, Canhão H, Fonseca JE. (2013) Old drugs old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs? BMC Med. 11:17.

Vale A, Pereira M, Maurício A, Vidal B, Rodrigues A, Caetano-Lopes J, Nazarian A, Fonseca J, Canhão H, Vaz M.(2013) Micro-computed tomography assessment of human femoral trabecular bone for two disease groups (fragility fracture and coxarthrosis): age and gender related effects on the microstructure. Journal of Biomedical Science and Engineering 6:175-184.

Costa N, Pires AE, Gabriel AM, Goulart LF, Pereira C, Leal B, Queiros AC, Chaara W, Moraes-Fontes MF, Vasconcelos C, Ferreira C, Martins J, Bastos M, Santos MJ, Pereira MA, Martins B, Lima M, João C, Six A, Demengeot J, Fesel C. (2013) Broadened T-cell repertoire diversity in IvIg-treated SLE patients is also related to the individual status of regulatory T-cells. J Clin Immunol. 33:349-60.

Moura RA, Canhão H, Polido-Pereira J, Rodrigues AM, Navalho M, Mourão AF, Resende C, Campanilho-Marques R, Dias JM, da Silva JA, Graca L, Fonseca JE. (2013) BAFF and TACI Gene Expression Are Increased in Patients with Untreated Very Early Rheumatoid Arthritis. J Rheumatol. 40: 1293-302

Navalho M, Resende C, Rodrigues AM, Pereira da Silva JA, Fonseca JE, Campos J, Canhão H. (2013) Bilateral evaluation of the hand and wrist in untreated early inflammatory arthritis: a comparative study of ultrasonography and magnetic resonance imaging. J Rheumatol 40: 1282-92.

Plenge RM, Greenberg JD, Mangravite LM, Derry JM, Stahl EA, Coenen MJ, Barton A, Padyukov L, Klareskog L, Gregersen PK, Mariette X,Moreland LW, Bridges SL Jr, de Vries N, Huizinga TW, Guchelaar HJ; International Rheumatoid Arthritis Consortium (INTERACT), Friend SH,Stolovitzky G. Collaborators: Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Mirkov, Canhao H, Ikari K, Terao C, Okada Y, Wedrï S, Askling J, Yamanaka H,Momohara S, Taniguchi A, Ohmura K, Matsuda F, Mimori T, Gupta N, Kuchroo M, Morgan AW, Isaacs JD, Wilson AG, Hyrich KL,Herenius M, Doorenspleet ME, Tak PP, Crusius JB, van der Horst-Bruinsma IE, Wolbink GJ, van Riel PL, van de Laar M, Guchelaar HJ,Shadick NA, Allaart CF, Huizinga TW, Toes RE, Kimberly RP, Bridges S Jr, Criswell LA, Moreland LW, Fonseca E, de Vries N,Raychaudhuri S, Weinblatt ME, Gregersen PK, Mariette X, Barton A, Alfredsson L, Klareskog L, Padyukov L, Coenen MJ, Karlson EW,Kremer J, Greenberg JD, Plenge RM. (2013) Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge. Nat Genet 45:468-9.

Vale AC, Faustino J, Reis L, Lopes A, Vidal B, Monteiro J, Fonseca JE, Canhao H, Vaz MF. (2013) Effects of the Shear Strain Rate on the Torsion of Human Trabecular Bone. J Biomech Eng. 135: 121005

Lin C, Karlson EW, Canhao H, Miller TA, Dligach D, Chen PJ, Perez RN, Shen Y, Weinblatt ME, Shadick NA, Plenge RM, Savova GK. (2013) Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records. PLoS One. 8(8):e69932.

Vale AC, Aleixo IP, Lúcio M, Saraiva A, Caetano-Lopes J, Rodrigues A, Amaral PM, Rosa LG, Monteiro J, Fonseca JE, Vaz MF, Canhão H. (2013) At the moment of occurrence of a fragility hip fracture, men have higher mechanical properties values in comparison with women.BMC Musculoskelet Disord 14:295.

Cáliz R, Canet LM, Lupiañez CB, Canhão H, Escudero A, Filipescu I, Segura-Catena J, Soto-Pino MJ, Expósito-Ruiz M, Ferrer MÁ, García A, Romani L, González-Utrilla A, Vallejo T, Pérez-Pampin E, Hemminki K, Försti A, Collantes E, Fonseca JE, Sainz J. (2013) Gender-Specific Effects of Genetic Variants within Th1 and Th17 Cell-Mediated Immune Response Genes on the Risk of Developing Rheumatoid Arthritis. PLoS One. 8(8):e72732.

Laires PA, Mesquita R, Veloso L, Martins AP, Cernadas R, Fonseca JE. (2013) Patient’s access to healthcare and treatment in rheumatoid arthritis: the views of stakeholders in Portugal. BMC Musculoskelet Disord 14:279.

Bettencourt BF, Rocha FL, Alves H, Amorim R, Caetano-Lopes J, Vieira-Sousa E, Pimentel-Santos F, Lima M, Porto G, Branco JC, Fonseca JE, Bruges-Armas J. (2013) Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals. Rheumatology (Oxford). 52: 2168-76.

Gonçalves MJ, Rodrigues AM, Canhão H, Fonseca JE.(2013) Osteoporosis: From Bone Biology to Individual Treatment Decision. Acta Med Port. 26:445-455.

Fonseca JE. (2013) Biobanco-IMM, Lisbon Academic Medical Centre: A Case Study. Acta Med Port. 26:312-4.

Reis C, Mestre C, Canhão H. (2013) Prevalence of fatigue in a group of airline pilots. Aviat Space Environ Med. 84:828-33.

Marques A, Mota A, Canhão H, Romeu JC, Machado P, Ruano A, Barbosa AP, Dias AA, Silva D, Araújo D, Simões E, Aguas F, Rosendo I, Silva I, Crespo J, Alves JD, Costa L, Mascarenhas M, Lourenço O, Ferreira PL, Lucas R, Roque R, Branco JC, Tavares V, Johansson H, Kanis J, Pereira da Silva JA. A FRAX model for the estimation of osteoporotic fracture probability in Portugal. Acta Reumatol Port. 38:104-112

Santos MJ (2013) Systemic rheumatic diseases: beyond classification criteria. Acta Reumatol Port. 38:7-8.

C. Ponte, E. Vieira-Sousa, F. Saraiva, R. Sousa, A. Francisco, S. Livraghi, J.C. Romeu, J.A. Pereira da Silva.(2013) Acute Low Back Pain – A Clinical and Imaging Challenge. Acta Reumatol Port. 2:133-135.

2014

Madruga Dias JA, Rosa RS, Perpétuo I, Rodrigues AM, Janeiro A, Costa MM, Gaião L, Pereira da Silva JA, Fonseca JE, Miltenberger-Miltenyi G.(2014) Pachydermoperiostosis in an African patient caused by a Chinese/Japanese SLCO2A1 mutation-Case report and review of literature. Semin Arthritis Rheum 43: 566-9.

Caetano-Lopes J, Rodrigues A, Lopes A, Vale AC, Pitts-Kiefer MA, Vidal B, Perpétuo IP, Monteiro J, Konttinen YT, Vaz MF, Nazarian A, Canhão H, Fonseca JE.(2014) Rheumatoid Arthritis Bone Fragility Is Associated With Upregulation of IL17 and DKK1 Gene Expression. Clin Rev Allergy Immunol. 47: 38-45.

Gonçalves MJ, Romão VC. Images in clinical medicine. (2014) Saber tibia in Paget’s disease of bone. N Engl J Med. 371:2417.

Cascão R, Vidal B, Raquel H, Neves-Costa A, Figueiredo N, Gupta V, Fonseca JE, Moita LF. (2014) Potent anti-inflammatory and antiproliferative effects of gambogic acid in a rat model of antigen-induced arthritis. Mediators Inflamm. 2014:195327.

Alonso-Perez E, Suarez-Gestal M, Calaza M, Blanco FJ, Suarez A, Santos MJ, Papasteriades C, Carreira P, Pullmann R, Ordi-Ros J, Marchini M, Skopouli FN, Bijl M, Barrizone N, Sebastiani GD, Migliaresi S, Witte T, Lauwerys BR, Kovacs A, Ruzickova S, Gomez-Reino JJ, Gonzalez A; European Consortium of SLE DNA Collections. (2014) Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus. Arthritis Res Ther 16 (3):R128.

Freira S, Fonseca H, Ferreira PD, Vasconcelos P, Fonseca JE. (2014) SAPHO Syndrome in an Adolescent: A Clinical Case With Unusual Severe Systemic Impact. J Adolesc Health 55:304-6.

Sanches BF, Martins T, Santos MJ, Azeredo P. Acute acalculous cholecystitis in a patient with juvenile dermatomyositis. (2014) BMJ Case Rep. 19; pii: bcr2014205066

Romão VC, Lima A, Bernardes M, Canhão H, Fonseca JE. (2014) Three decades of low-dose methotrexate in rheumatoid arthritis: Can we predict toxicity? Imunol Res 60:289-310

Mourão AF, Santos MJ, Melo-Gomes J, Martins FM, Costa JA, Ramos F, Brito I, Duarte C, Figueira R, Figueiredo G, Furtado C, Lopes A, Oliveira M, Rodrigues A, Salgado M, Sousa M, Branco JC, Fonseca JE, Canhão H. (2014) Using the juvenile arthritis disease activity score based on erythrocyte sedimentation rate or C-reactive protein level: results from the portuguese register. Arthritis Care Res (Hoboken) 66:585-91.

Cambridge G, Moura RA, Santos T, Khawaja AA, Polido-Pereira J, Canhão H, Leandro MJ, Fonseca JE. (2014) Expression of the inherently autoreactive idiotope 9G4 on autoantibodies to citrullinated peptides and on rheumatoid factors in patients with early and established rheumatoid arthritis. PLoS One 9(9):e107513.

Lucas R, Ramos E, Prata M, Rodrigues AM, Costa L, Severo M, Canhão H, Fonseca JE, Barros H. (2014) Changes in serum RANKL and OPG with sexual development and their associations with bone turnover and bone mineral density in a cohort of girls. Clin Biochem 47:1040-6.

Okada Y, Diogo D, Greenberg JD, Mouassess F, Achkar WA, Fulton RS, Denny JC, Gupta N, Mirel D, Gabriel S, Li G, Kremer JM, Pappas DA, Carroll RJ, Eyler AE, Trynka G, Stahl EA, Cui J, Saxena R, Coenen MJ, Guchelaar HJ, Huizinga TW, Dieudé P, Mariette X, Barton A, Canhão H, Fonseca JE, de Vries N, Tak PP, Moreland LW, Bridges SL Jr, Miceli-Richard C, Choi HK, Kamatani Y, Galan P, Lathrop M, Raj T, De Jager PL, Raychaudhuri S, Worthington J, Padyukov L, Klareskog L, Siminovitch KA, Gregersen PK, Mardis ER, Arayssi T, Kazkaz LA, Plenge RM. (2014) Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene. PLoS One 9(2):e87645.

Campanilho-Marques R, Ramos F, Canhão H, Fonseca JE. (2014) Remission induced by infliximab in a childhood polyarteritis nodosa refractory to conventional immunosuppression and rituximab. Joint Bone Spine 81:277-8.

Kearsley-Fleet L, Závada J, Hetland ML, Nordström DC, Aaltonen KJ, Listing J, Zink A, Gati T, Rojkovich B, Iannone F, Gremese E, van Riel PL, van de Laar MA, Lie E, Kvien TK, Canhão H, Fonseca JE, Rotar Z, Loza E, Carmona L, Askling J, Johansson K, Finckh A, Dixon WG, Hyrich KL; on behalf of the EULAR Study Group for Registers and Observational Drug Studies. (2014) The EULAR Study Group for Registers and Observational Drug Studies: comparability of the patient case mix in the European biologic disease modifying anti-rheumatic drug registers. Rheumatology (Oxford) 54: 1074-9.

Campanilho-Marques R, Bogas M, Ramos F, Santos MJ, Fonseca JE. (2014) Prognostic value of antinuclear antibodies in juvenile idiopathic arthritis and anterior uveitis. Results from a systematic literature review. Acta Reumatol Port 39:116-22.

Araújo F, Cordeiro I, Teixeira F, Rovisco J, Ramiro S, Mourão AF, Costa JA, Pimentão JB, Malcata A, Santos MJ, Branco JC. (2014) Portuguese Recommendations for the Diagnosis and Management of Gout. Acta Reumatol Port 39:158-71

Araújo F, Cordeiro I, Teixeira F, Gonçalves J, Fonseca JE.(2014) Pharmacology of biosimilar candidate drugs in rheumatology: a literature review. Acta Reumatol Port. 39:19-26.

Dias JM, Costa MM, Canhão H, Saraiva F, Silva JA. (2014) Musculoskeletal ultrasound in Paediatric Rheumatology: a retrospective analysis. Acta Reumatol Port 39: 309-14.

Fonseca JE, Gonçalves J, Araújo F, Cordeiro I, Teixeira F, Canhão H, da Silva JA, Garcês S, Miranda LC, Ramiro S, Roxo A, Pimentel-Santos FM, Tavares V, Neto A, Sepriano A, Malcata A, Faustino A, Silva C, Ambrósio C, Duarte C, Miguel C, Barcelos F, Santos H, Cunha I, Ramos JC, Gomes JA, Pimentão JB, CostaL, Maurício L, Silva M, Bernardes M, Bogas M, Coelho PC, Monteiro P, Aguiar R, André R, Leitão R, Pimenta S, Meirinhos T, Fernandes S, Las V, Castelão W; Sociedade Portuguesa de Reumatologia. (2014) The Portuguese Society of Rheumatology position paper on the use of biosimilars. Acta Reumatol Port 39:60-71.

Fonseca JE.(2014) Revisiting rheumatic diseases and cancer.Acta Reumatol Port 39:9-10.

Ferraria N, Marques JG, Ramos F, Lopes G, Fonseca JE, Neves MC.(2014) Chronic recurrent multifocal osteomyelitis: case series of four patients treated with biphosphonates. Acta Reumatol Port 39:38-45.

Campanilho-Marques R, Ramos F, Canhão H, Fonseca JE. Remission induced by infliximab in a childhood polyarteritis nodosa refractory to conventional immunosuppression and rituximab. Joint, bone, spine : revue du rhumatisme. 2014; 81(3):277-8.

Campanilho-Marques R, Novelli V, Brogan PA, Eleftheriou D. Polyarticular septic arthritis in an 11-year-old child. Clinical rheumatology. 2014; 33(8):1181-2.

Campanilho-Marques R, Brogan PA. Mevalonate kinase deficiency in two sisters with therapeutic response to anakinra: case report and review of the literature. Clinical rheumatology. 2014; 33(11):1681-4.

Ponte C, Macieira C. (2014) Beyond an inflamed ear. Acta Med Port 27:790.

2015

Martins FM, da Silva JA, Santos MJ, Vieira-Sousa E, Duarte C, Santos H, Costa JA, Pimentel-Santos FM, Cunha I, Cunha Miranda L, Nóvoa T, Cruz M, Bernardes M, Araujo D, Pereira Silva JA, Silva JC, Branco JC, Gomes JA, Faustino A, Fonseca JE, Canhão H. (2015) DAS28, CDAI and SDAI cut-offs do not translate thesame information: results from the Rheumatic Diseases Portuguese Register Reuma.pt. Rheumatology (Oxford) 54: 286-91.

Gonçalves MJ, Sousa S, Inês LS, Duarte C, Borges J, Silva C, Romão VC, Terroso G, Bernardes M, Cerqueira M, Raposo A, Sequeira G, Barcelos A, Macieira C, Canas da Silva J, Costa L, Pereira da Silva JA, Cunha-Miranda L, Da Silva JA, Canhão H, Santos MJ. (2015) Characterization of damage in Portuguese lupus patients: analysis of a national lupus registry. Lupus 24: 256-62.

Araujo GR, Fonseca JE, Fujimura PT, Cunha-Junior JP, Silva CH, Mourão AF, Canhão H, Goulart LR, Gonçalves J, Ueira-Vieira C. (2015) Anti-type II collagen antibodies detection and avidity in patients with oligoarticular and polyarticular forms of juvenile idiopathic arthritis. Immunol Lett 165 :20-5

Canhão H, Rodrigues AM, Santos MJ, Carmona-Fernandes D, Bettencourt BF, Cui J, Rocha FL, Canas Silva J, Polido-Pereira J, Pereira Silva JA, Costa JA, Araujo D, Silva C, Santos H, Duarte C, Cáliz R, Filipescu I, Pimentel-Santos F, Branco J, Sainz J, Plenge RM, Solomon DH, Bruges-Armas J, Da Silva JA, Fonseca JE, Karlson EW. (2015) TRAF1/C5 but Not PTPRC Variants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy. Biomed Res Int. 2015:490295

Diogo D, Bastarache L, Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S, Bowes J, Cui J, Lee A, Pappas DA, Kremer JM, Barton A, Coenen MJ, Franke B, Kiemeney LA, Mariette X, Richard-Miceli C, Canhão H, Fonseca JE, de Vries N, Tak PP, Crusius JB, Nurmohamed MT, Kurreeman F, Mikuls TR, Okada Y, Stahl EA, Larson DE, Deluca TL, O’Laughlin M, Fronick CC, Fulton LL, Kosoy R, Ransom M, Bhangale TR, Ortmann W, Cagan A, Gainer V, Karlson EW, Kohane I, Murphy SN, Martin J, Zhernakova A, Klareskog L, Padyukov L, Worthington J, Mardis ER, Seldin MF, Gregersen PK, Behrens T, Raychaudhuri S, Denny JC, Plenge RM. (2015) TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits. PLoS One 10(4):e0122271.

Canet LM, Filipescu I, Cáliz R, Lupiañez CB, Canhão H, Escudero A, Segura-Catena J, Soto-Pino MJ, Ferrer MA, García A, Romani L, Pérez-Pampin E, González-Utrilla A, López Nevot MA, Collantes E, Fonseca JE, Sainz J. (2015) Genetic variants within the TNFRSF1B gene and susceptibility to rheumatoid arthritis and response to anti-TNF drugs: a multicenter study. Pharmacogenet Genomic 25 :323-33

Yeremenko N, Zwerina K, Rigter G, Pots D, Fonseca J, Zwerina J, Schett G, Baeten D. (2015) TNF-α and IL-6 differentially regulate Dkk-1 in the inflamed arthritic joint. Arthritis Rheumatol 67:2071-5

Smolen JS, Breedveld FC, Burmester GR, Bykerk V, Dougados M, Emery P, Kvien TK, Navarro-Compán MV, Oliver S, Schoels M, Scholte-Voshaar M, Stamm T, Stoffer M, Takeuchi T, Aletaha D, Andreu JL, Aringer M, Bergman M, Betteridge N, Bijlsma H, Burkhardt H, Cardiel M, Combe B, Durez P, Fonseca JE, Gibofsky A, Gomez-Reino JJ, Graninger W, Hannonen P, Haraoui B, Kouloumas M, Landewe R, Martin-Mola E, Nash P, Ostergaard M, Östör A, Richards P, Sokka-Isler T, Thorne C, Tzioufas AG, van Vollenhoven R, de Wit M, van der Heijde D. (2015) Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis 75:3-15.

Almeida B, Campanilho-Marques R, Arnold K, Pilkington CA, Wedderburn LR, Nistala K. Analysis of Published Criteria for Clinically Inactive Disease in a Large Juvenile Dermatomyositis Cohort Shows That Skin Disease Is Underestimated. Arthritis & rheumatology (Hoboken, N.J.). 2015; 67(9):2495-502.

Romão VC, Santos MJ, Polido-Pereira J, Duarte C, Nero P, Miguel C, Costa JA, Bernardes M, Pimentel-Santos FM, Barcelos F, Costa L, Melo Gomes JA, Pereira da Silva JA, Branco JC, Canas da Silva J, Pereira da Silva JA, Fonseca JE, Canhão H. (2015) Comparative Effectiveness of Tocilizumab and TNF Inhibitors in Rheumatoid Arthritis Patients: Data from the Rheumatic Diseases Portuguese Register, Reuma.pt. Biomed Res Int 2015:279890.

Araujo GR, Vaz ER, Fujimura PT, Fonseca JE, de Lima LM, Canhão H, Venturini G, Cardozo KH, Carvalho VM, Napimoga MH, Goulart LR, Gonçalves J, Ueira-Vieira C. (2015) Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of Carbonic Anhydrase III selected in a murine model by phage display. Arthritis Res Ther 17:168.

Vieira-Sousa E, van Duivenvoorde LM, Fonseca JE, Lories RJ, Baeten DL. (2015) Animal models as a tool to dissect pivotal pathways driving spondyloarthritis. Arthritis Rheumatol 67:2813-27.

Rodrigues AM, Gouveia N, Costa LP, Eusébio M, Ramiro S, Machado P, Mourão AF, Silva I, Laires P, Sepriano A, Araújo F, Coelho PS, Gonçalves S, Zhao A, Fonseca JE, Almeida JM, Tavares V, da Silva JA, Barros H, Cerol J, Mendes J, Carmona L, Canhão H, Branco JC. EpiReumaPt- the study of Rheumatic and Musculoskeletal diseases in Portugal: A detailed view of the methodology. Acta Reumatol Port 40:110-124.

Mourão AF, Santos MJ, Mendonça S, Oliveira-Ramos F, Salgado M, Estanqueiro P, Melo-Gomes J, Martins F, Lopes A, Bettencourt BF, Bruges-Armas J, Costa J, Furtado C, Figueira R, Brito I, Branco J, Fonseca JE, Canhão H. (2015) Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiopathic Arthritis: Data from Reuma.pt. J Immunol Res 2015:706515

Laires PA, Dezerto R, Mesquita R, Fonseca JE, Cernadas R, Miranda LC, Silva JC, Costa L, Nogueira AM. (2015) Effectiveness of A Referral Program for Early Arthritis Diagnosis At Primary Care Centers in Portugal – Preliminary Results from the Siara Study. Value Health 18:A658.

Vieira-Sousa E, Machado PM, Costa J, Ribeiro A, Aguiar R, Cerqueira M, Neto A, Bernardo A, Cordeiro A, Duarte C, Vinagre F, Canhão H, Santos H, Neves JS, Cunha-Miranda L, Silva M, Santos MJ, Bernardes M, Bogas M, Abreu P, Viana-Queiroz M, Barros R, Falcão S, Pimenta S, Teixeira V, Fonseca JE, Barcelos A. (2015) Portuguese recommendations for the use of biological therapies in patients with psoriatic arthritis – 2015 update. Acta Reumatol Port 40:275-290.

Cascão R, Vidal B, Lopes IP, Paisana E, Rino J, Moita LF, Fonseca JE. (2015) Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats. PLoS One 10(12):e0142448

Perpétuo IP, Raposeiro R, Caetano-Lopes J, Vieira-Sousa E, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE. (2015) Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Ankylosing Spondylitis. PLoS One 10(12):e0144655.

Vidal B, Cascão R, Vale AC, Cavaleiro I, Vaz MF, Brito JA, Canhão H, Fonseca JE. Arthritis induces early bone high turnover, structural degradation and mechanical weakness. PLoS One 10(1):e0117100

Traunecker E, Gardner R, Fonseca JE, Polido-Pereira J, Seitz M, Villiger PM, Iezzi G, Padovan E. Blocking of LFA-1 enhances expansion of Th17 cells induced by human CD14(+) CD16(++) nonclassical monocytes. Eur J Immunol. 45:1414-25.

Kearsley-Fleet L, Závada J, Hetland ML, Nordström DC, Aaltonen KJ, Listing J, Zink A, Gati T, Rojkovich B, Iannone F, Gremese E, van Riel PL, van de Laar MA, Lie E, Kvien TK, Canhão H, Fonseca JE, Rotar Ž, Loza E, Carmona L, Askling J, Johansson K, Finckh A, Dixon WG, Hyrich KL; EULAR Study Group for Registers and Observational Drug Studies. (2015) The EULAR Study Group for Registers and Observational Drug Studies: comparability of the patient case mix in the European biologic disease modifying anti-rheumatic drug registers. Rheumatology (Oxford). 54:1074-9

Martins FM, da Silva JA, Santos MJ, Vieira-Sousa E, Duarte C, Santos H, Costa JA, Pimentel-Santos FM, Cunha I, Cunha Miranda L, Nóvoa T, Cruz M, Bernardes M, Araujo D, Pereira Silva JA, Silva JC, Branco JC, Gomes JA, Faustino A, Fonseca JE, Canhão H. (2015) DAS28, CDAI and SDAI cut-offs do not translate the same information: results from the Rheumatic Diseases Portuguese Register Reuma.pt. Rheumatology (Oxford) 54:286-91.

Pires J, Gonçalves MJ, Costa A, Pereira A, Gonçalves A, Romeu JC. (2015) Polyarteritis nodosa: the angiography usefulness. Acta Reumatol Port 40:193-4.

Gonçalves MJ, Sousa S, Inês LS, Cunha-Miranda L, Canhão H, Santos MJ. (2015) The weaker sex: Characterization of gender disparities in a nationwide lupus register (Reuma.pt/SLE). Joint Bone Spine 82:378-80.

Gouveia N, Rodrigues AM, Ramiro S, Machado P, da Costa LP, Mourão AF, Silva I, Rego T, Laires P, André R, Mauricio L, Romeu JC, Tavares V, Cerol J, Canhão H, Branco JC. (2015) How to perform a national population based study – a practical guide. Acta Reumatol Port 40:128-136.

Inês L, Silva C, Galindo M, López-Longo FJ, Terroso G, Romão VC, Rúa-Figueroa I, Santos MJ, Pego-Reigosa JM, Nero P, Cerqueira M, Duarte C, Miranda LC, Bernardes M, Gonçalves MJ, Mouriño-Rodriguez C, Araújo F, Raposo A, Barcelos A, Couto M, Abreu P, Otón-Sanchez T, Macieira C, Ramos F, Branco JC, Silva JA, Canhão H, Calvo-Alén J; for the Rheumatic Diseases Registry of the Portuguese Society of Rheumatology (Reuma.pt) and for the Registry of SLE Patients of the Spanish Society of Rheumatology (RELESSER). (2015) Classification of Systemic lupus erythematosus: Systemic Lupus International Collaborating Clinics versus American College of Rheumatology criteria. Arthritis Care Res (Hoboken) 67: 1180-5.

Loureiro M, Sousa S, Santos MJ. (2015) Esclerose sistémica juvenil. Acta Med Port 28:785-78.

Romão VC, Pitzalis C. (2015) Synovial heterogeneity in rheumatoid arthritis: the key for rational patient stratification? Acta Reumatol Port 40:6-8.

Finckh A, Neto D, Iannone F, Loza E, Lie E, van Riel P, Hetland ML, Pavelka K, Gottenberg JE, Canhão H, Mariette X, Turesson C. (2015) The impact of patient heterogeneity and socioeconomic factors on abatacept retention in rheumatoid arthritis across nine European countries. RMD Open 1(1):e000040.

Walker UA, Jaeger VK, Chatzidionysiou K, Hetland ML, Hauge EM, Pavelka K, Nordström DC, Canhão H, Tomšič M, van Vollenhoven R, Gabay C. (2016) Rituximab done: what’s next in rheumatoid arthritis? A European observational longitudinal study assessing the effectiveness of biologics after rituximab treatment in rheumatoid arthritis. Rheumatology (Oxford) 55: 230-6.

Canet LM, Cáliz R, Lupiañez CB, Canhão H, Martinez M, Escudero A, Filipescu I, Segura-Catena J, Soto-Pino MJ, Ferrer MA, García A, Romani L, Pérez-Pampin E, González-Utrilla A, López Nevot MÁ, Collantes E, Fonseca JE, Sainz J. (2015) Genetic variants within immune-modulating genes influence the risk of developing rheumatoid arthritis and anti-TNF drug response: a two-stage case-control study. Pharmacogenet Genomics 25:432-43.

Branco JC, Canhão H. (2015) EpiReumaPt – development and consequences. Acta Reumatol Port 40:106-109.

Oliveira P, Zejnilovic L, Canhão H, von Hippel E. (2015) Innovation by patients with rare diseases and chronic needs. Orphanet J Rare Dis 10:41

Laires PA, Canhão H, Gouveia M. (2015) Indirect costs associated with early exit from work attributable to rheumatic diseases. Eur J Public Health 25:677-82

Fernandes S, Capela S, Resende C, Romeu JC, Pereira da Silva JA. (2015) Severe vertical atlanto-axial subluxation in rheumatoid arthritis. Acta Reumatol Port 40:91-92.

Fernandes S, Romeu JC, Pereira da Silva JA. (2015) Platelet Rich Plasma: What should the rheumatologist expect? Acta Reumatol Port 40: 214-222.

2016

Gabay C, Riek M, Hetland ML, Hauge EM, Pavelka K, Tomšič M, Canhao H, Chatzdionysiou K, Lukina G, Nordström DC, Lie E, Ancuta I, Hernández MV, van Riel PL, van Vollenhoven R, Kvien TK. (2016) Effectiveness of tocilizumab with and without synthetic disease-modifying antirheumatic drugs in rheumatoid arthritis: results from a European collaborative study. Ann Rheum Dis 75: 1336-42

Mourão AF, Santos MJ, Melo Gomes JA, Martins FM, Mendonça SC, Oliveira Ramos F, Fernandes S, Salgado M, Guedes M, Carvalho S, Costa JA, Brito I, Duarte C, Furtado C, Lopes A, Rodrigues A, Sequeira G, Branco JC, Fonseca JE, Canhão H. (2016) Effectiveness and long-term retention of anti-tumour necrosis factor treatment in juvenile and adult patients with juvenile idiopathic arthritis: data from Reuma.pt. Rheumatology (Oxford) 55:697-703.

Gouveia N, Rodrigues A, Eusébio M, Ramiro S, Machado P, Canhão H, Branco JC. (2016) Prevalence and social burden of active chronic low back pain in the adult Portuguese population: results from a national survey. Rheumatol Int 36: 183-97.

Humby F, Kelly S, Bugatti S, Manzo A, Filer A, Mahto A, Fonseca JE, Lauwerys B, D’Agostino MA, Naredo E, Lories R, Montecucco C, Tak PP, Fitzgerald O, Smith MD, Veale DJ, Choy EH, Strand V, Pitzalis C. (2016) Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter-determining Validation Requirements. J Rheumatol 43: 208-13.

Araujo F, Goncalves J, Fonseca JE. (2016) Biosimilar DMARDs: What Does the Future Hold? Drugs 76: 629-637.

Araujo GR, Fujimura PT, Vaz ER, Silva TA, Rodovalho VR, Britto-Madurro AG, Madurro JM, Fonseca JE, Silva CHM, Santos PS, Mourao AF, Canhao H, Goulart LR, Goncalves J, Ueira-Vieira C. (2016) A novel reactive epitope-based antigen targeted by serum autoantibodies in oligoarticular and polyarticular juvenile idiopathic arthritis and development of an electrochemical biossensor. Immunobiology 224:634-640.

Araujo FC, Goncalves J, Fonseca, JE. (2016) Pharmacoeconomics of Biosimilars: What Is There to Gain from Them? Curr Rheumatol Rep. 18: 50.

Gonçalves J, Araújo F, Cutolo M, Fonseca JE. (2016) Biosimilar monoclonal antibodies: preclinical and clinical development aspects. Clin Exp Rheumatol 34: 698-705.

Barreira SC, Fonseca JE. (2016) The Impact of Conventional and Biological Disease Modifying Antirheumatic Drugs on Bone Biology. Rheumatoid Arthritis as a Case Study. Clin Rev Allergy Immunol. 51:100-109.

Santos MJ, Canhao H, Faustino A, Fonseca JE. (2016) Reuma.pt: A Case Study. Acta Med Port 29:83-84.

Xerinda S, Oliveira O, Lucas R, Fonseca JE, Varela P, Cotter J, Duarte R. (2016) Gaps and barriers to tuberculosis screening among anti-tumor necrosis factor prescribers. Acta Reumatol Port 41: 382-4.

Castro AM, Fernandes DC, Rodrigues AM, Pedro LM, Santos MJ, Canhão H, Fonseca JE. (2016) Incidence and predictors of cardiovascular events in a cohort of patients with rheumatoid arthritis. Acta Reumatol Port 41:213-219.

Fernandes S, Vieira-Sousa E, Furtado C, Costa A, Barros R, Fonseca JE. (2016) A diagnosis of disseminated tuberculosis based on knee arthroscopic guided synovial biopsy in the context of monoarthritis. Acta Reumatol Port 4:256-259.

Santos MJ, Conde M, Mourão AF, Ramos FO, Cabral M, Brito I, Ramos MP, Marques RC, Gomes SM, Guedes M, Gonçalves MJ, Estanqueiro P, Zilhão C, Rodrigues M, Henriques C, Salgado M, Canhão H, Fonseca JE, Gomes JM. (2016) 2016 update of the Portuguese recommendations for the use of biological therapies in children and adolescents with Juvenile Idiopathic Arthritis. Acta Reumatol Port 41:194-212.

Oliveira-Ramos F, Eusébio M, M Martins F, Mourão AF, Furtado C, Campanilho-Marques R, Cordeiro I, Ferreira J, Cerqueira M, Figueira R, Brito I, Canhão H, Santos MJ, Melo-Gomes JA, Fonseca JE. (2016) Juvenile idiopathic arthritis in adulthood: fulfilment of classification criteria for adult rheumatic diseases, long-term outcomes and predictors of inactive disease, functional status and damage. RMD Open 2(2):e000304.

Azevedo V, Hassett B, Fonseca JE, Atsumi T, Coindreau J, Jacobs I, Mahgoub E, O’Brien J, Singh E, Vicik S, Fitzpatrick B. (2016) Differentiating biosimilarity and comparability in biotherapeutics. Clin Rheumatol 35: 2877-86.

Fernandes S, Almeida P, Melo-Gomes J, Romeu JC. (2016) Brown Tumors in Secondary Hyperparathyroidism in a Patient With Lupus Nephritis J Clin Rheumatol 22: 438-439.

Marques A, Rodrigues AM, Romeu JC, Ruano A, Barbosa AP, Simões E, Águas F, Canhão H, Alves JD, Lucas R, Branco JC, Laíns J, Mascarenhas M, Simões S, Tavares V, Lourenço O, da Silva JA. (2016) Multidisciplinary Portuguese recommendations on DXA request and indication to treat in the prevention of fragility fractures. Acta Reumatol Port 2016; 41: 305-321.

Sousa S, Gonçalves MJ, Inês LS, Eugénio G, Jesus D, Fernandes S, Terroso G, Romão VC, Cerqueira M, Raposo A, Couto M, Nero P, Sequeira G, Nóvoa T, Melo Gomes JA, da Silva JC, Costa L, Macieira C, Silva C, Silva JA, Canhão H, Santos MJ. (2016) Clinical features and long-term outcomes of systemic lupus erythematosus: comparative data of childhood, adult and late-onset disease in a national register. Rheumatol Int 36: 955-60.

Cordeiro I, Duarte AC, Ferreira JF, Gonçalves MJ, Meirinhos T, Rocha TM, Romão VC, Sousa S, Guedes M, Conde M, Abreu C, Aleixo MJ, Santos MJ. (2016) Recommendations for Vaccination in Adult Patients with Systemic Inflammatory Rheumatic Diseases from the Portuguese Society of Rheumatology. Acta Reumatol Port 41: 112-130.

Cortes M, Fernandes S, Teixeira V. (2016) Upper gastrointestinal bleeding in a patient with Sjögren syndrome. Rev Esp Enferm Dig. 108:576.

Barreto Cortes M, Teixeira V, Fernandes SR, Rego F. (2016) Haemophilus parainfluenzae endocarditis with systemic embolisation following maxillary sinusitis. BMJ Case Rep. 2016 -216473.

Smolen JS, Breedveld FC, Burmester GR, Bykerk V, Dougados M, Emery P, Kvien TK, Navarro-Compán MV, Oliver S, Schoels M, Scholte-Voshaar M, Stamm T, Stoffer M, Takeuchi T, Aletaha D, Andreu JL, Aringer M, Bergman M, Betteridge N, Bijlsma H, Burkhardt H, Cardiel M, Combe B, Durez P, Fonseca JE, Gibofsky A, Gomez-Reino JJ, Graninger W, Hannonen P, Haraoui B, Kouloumas M, Landewe R, Martin-Mola E, Nash P, Ostergaard M, Östör A, Richards P, Sokka-Isler T, Thorne C, Tzioufas AG, van Vollenhoven R, de Wit M, van der Heijde D. (2016) Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force. Ann Rheum Dis 75:3-15.

Bentow C, Lakos G, Martis P, Wahl E, Garcia M, Viñas O, Espinosa G, Cervera G, Sjowall G, Carmona-Fernandes D, Santos MJ, Hanly JG, Mahler M. (2016) International multi-center evaluation of a novel chemiluminescence assay for the detection of anti-dsDNA antibodies. Lupus 25:864-72.

Almeida S, Braga M, Santos MJ. (2016) Juvenile dermatomyositis with anti-signal recognition particle antibodies: a case report. Acta Reumatol Port 41:162-4.

Courvoisier DS, Alpizar-Rodriguez D, Gottenberg JE, Hernandez MV, Iannone F, Lie E, Santos MJ, Pavelka K, Turesson C, Mariette X, Choquette D, Hetland ML, Finckh A. (2016) Rheumatoid Arthritis Patients after Initiation of a New Biologic Agent: Trajectories of Disease Activity in a Large Multinational Cohort Study. EBioMedicine. 11:302-306.

Teixeira L, Fonseca AR, Eugénio G, Rodrigues M, Khmelinskii N, Fernandes S, Serra S, Costa T, Santos MJ. (2016) Management of infections in rheumatic patients receiving biological therapies. The Portuguese Society of Rheumatology recommendations. Acta Reumatol Port 41: 287-304.

Campanilho-Marques R, Almeida B, Deakin C, Arnold K, Gallot N, de Iorio M, Nistala K, Pilkington CA, Wedderburn LR. (2016) Comparison of the utility and validity of three scoring tools to detect skin disease in patients with Juvenile Dermatomyositis. Arthritis Care Res 68: 1514–21.

Sepriano A, Ramiro S, van der Heijde D, Ávila-Ribeiro P, Fonseca R, Borges J, Teixeira L, Carvalho PD, Cerqueira M, Neves J, Meirinhos T, Barcelos A, Sequeira G, Salvador MJ, Canas da Silva J, Santos H, Bernardes M, Vieira-Sousa E, Canhão H, Branco JC, Pimentel-Santos F, Landewé R. (2016) Effect of Comedication With Conventional Synthetic Disease-Modifying Antirheumatic Drugs on Retention of Tumor Necrosis Factor Inhibitors in Patients With Spondyloarthritis: A Prospective Cohort Study. Arthritis Rheumatol 68:2671-9.

Tang MW, Reedquist KA, Garcia S, Fernandez BM, Codullo V, Vieira-Sousa E, Goffin V, Reuwer AQ, Twickler MT, Gerlag DM, Tak PP. (2016) The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation. Rheumatology (Oxford). 55: 2248-59.

Landi M, Maldonado-Ficco H, Perez-Alamino R, Maldonado-Cocco JA, Citera G, Arturi P, Sampaio-Barros PD, Flores Alvarado DE, Burgos-Vargas R, Santos E, Palleiro D, Gutiérrez MA, Vieyra-Sousa E, Pimentel-Santos F, Paira SO, Berman A, Barrezueta CV, Vazquez-Mellado J, Collantes-Estevez E; RESPONDIA Group. Fundación Reumatológica Argentina “Dr. Osvaldo García Morteo. (2016) Gender differences among patients with primary ankylosing spondylitis and spondylitis associated with psoriasis and inflammatory bowel disease in an iberoamerican spondyloarthritis cohort. Medicine (Baltimore) 295(51):e5652.

Vieira Sousa E, Sepriano A, Pimentel Santos F. (2016) Investigator initiated trials in Portuguese rheumatology. Acta Reumatol Port. 41:101-3.

2017

Sousa S, Duarte AC, Cordeiro I, Ferreira J, Gonçalves MJ, Meirinhos T, Rocha TM, Romão VC, Santos MJ. (2017) Efficacy and Safety of Vaccination in Pediatric Patients with Systemic Inflammatory Rheumatic Diseases: a systematic review of the literature. Acta Reumatol Port 2016; 42: 8-16.

Orr C, Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Le Goff B, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Thurlings R, Fonseca JE, Veale DJ. (2017) Synovial tissue research: a state-of-the-art review. Nat Rev Rheumatol 13:463-475.

Vieira-Sousa E, Cavaleiro J, Mourão AF, Rodrigues AM, Albino-Teixeira A, Pimentel-Santos FM, Oliveira-Ramos F, Canhão H, Polido-Pereira J, Fonseca JE, Pereira da Silva JA, Romeu JC, Melo Gomes J, Costa L, Graça L, Leandro MJ, Santos MJ, Machado PM, Ramiro S. (2017) Acta Reumatológica Portuguesa: perspectives in 2017. Acta Reumatol Port 42:110-111.

Cascão R, Fonseca JE, Moita LF. (2017) Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases. Front Med (Lausanne) 4:69.

Duarte AC, Santos-Faria D, Gonçalves MJ, Sepriano A, Mourão AF, Duarte C, Neves JS, Águeda AF, Ribeiro PÁ, Daniel A, Neto A, Cordeiro A, Rodrigues A, Barcelos A, Silva C, Ponte C, Vieira-Sousa E, Teixeira F, Oliveira-Ramos F, Araújo F, Barcelos F, Canhão H, Santos H, Ramos J, Pereira J, Costa J, Melo Gomes JA, Cunha-Miranda L, Costa L, Cerqueira M, Cruz M, Santos MJ, Bernardes M, Oliveira P, Abreu P, Figueira R, Barros R, Falcão S, Pinto P, Pimenta S, Capela S, Teixeira V, Fonseca JE. (2017) Portuguese recommendations for the use of methotrexate in rheumatic diseases – 2016 update. Acta Reumatol Port 42: 127-40.

Duarte C, Sousa-Neves J, Águeda A, Ribeiro P, Daniel A, Eugénio G, Serra S, Araújo F, Barcelos A, Filipe B, Bernardes M, Canhão H, Cerqueira M, Capela S, Cordeiro A, Costa F, Costa L, Cruz M, Cunha Miranda L, Duarte C, Falcão S, Faria D, Figueira R, Freitas JP, Gonçalves MJ, Madruga Dias J, Melo Gomes J, Mourão AF, Neto A, Oliveira Ramos F, Pimenta S, Pinto P, Polido Pereira J, Ponte C, Ramos J, Rodrigues A, Santos H, Santos MJ, Sepriano A, Silva C, Tavares Costa J, Teixeira F, Teixeira V, Valente P, Vieira-Sousa E, Barros R, Abreu P, Fonseca JE. (2017) Portuguese Recommendations for the use of biological therapies in patients with rheumatoid arthritis- 2016 update. Acta Reumatol Port 42: 112-26.

van Steenbergen HW, Aletaha D, Beaart-van de Voorde LJ, Brouwer E, Codreanu C, Combe B, Fonseca JE, Hetland ML, Humby F, Kvien TK, Niedermann K, Nuño L, Oliver S, Rantapää-Dahlqvist S, Raza K, van Schaardenburg D, Schett G, De Smet L, Szücs G, Vencovský J, Wiland P, de Wit M, Landewé RL, van der Helm-van Mil AH. (2017) EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis. Ann Rheum Dis 76:491-496.

Costa N, Marques O, Godinho SI, Carvalho C, Leal B, Figueiredo AM, Vasconcelos C, Marinho A, Moraes-Fontes MF, Gomes da Costa A, Ponte C, Campanilho-Marques R, Cóias T, Martins AR, Viana JF, Lima M, Martins B, Fesel C. (2017) Two separate effects contribute to regulatory T-cell defect in SLE patients and their unaffected relatives. Clin Exp Immunol 189: 318-330.

Germanò G, Monti S, Ponte C, Possemato N, Caporali R, Salvarani C, Macchioni P, Pipitone N. (2017) The role of ultrasound in the diagnosis and follow-up of large-vessel vasculitis: an update. Clin Exp Rheumatol 35 Suppl 103(1):194-198.

Azevedo V, Hassett B, Fonseca JE, Atsumi T, Coindreau J, Jacobs I, Mahgoub E, O’Brien J, Singh E, Vicik S, Fitzpatrick B. (2017) Differentiating biosimilarity and comparability in biotherapeutics. Clin Rheumatol 35:2877-2886.

Perpétuo IP, Caetano-Lopes J, Vieira-Sousa E, Campanilho-Marques R, Ponte C, Khmelinskii N, Canhão H, Ainola M, Fonseca JE. (2017) Ankylosing Spondylitis Patients Have Impaired Osteoclast Gene Expression in Circulating Osteoclast Precursors. Front Med 4:38.

Castro AM, Polido-Pereira J, Saraiva F, Pimentao JB, Romeu JC. (2017) Calcium Pyrophosphate Dihydrate Deposition in a Pseudarthrosis. A New Location for an Old Disease. J Clinical Rheumatol 23: 176-178.

Castro A, Romeu JC, Geraldes R, Pereira da Silva JA. (2017) Encephalopathy with upper body hypertonia and myoclonus in a patient with systemic lupus erythematosus and anti-CASPR2. Lupus 26: 84-87.

Cui J, Diogo D, Stahl EA, Canhao H, Mariette X, Greenberg JD, Okada Y, Pappas DA, Fulton RS, Tak PP, Nurmohamed MT, Lee A, Larson DE, Kurreeman F, Deluca TL, O’Laughlin M, Fronick CC, Fulton LL, Mardis ER, van der Horst-Bruinsma IE, Wolbink GJ, Gregersen PK, Kremer JM, Crusius JB, de Vries N, Huizinga TW, Fonseca JE, Miceli-Richard C, Karlson EW, Coenen MJ, Barton A, Plenge RM, Raychaudhuri S. (2017) The role of rare protein-coding variants to anti-TNF treatment response in rheumatoid arthritis. Arthritis Rheumatol 69:735-741.

Combe B, Landewe R, Daien CI, Hua C, Aletaha D, Álvaro-Gracia JM, Bakkers M, Brodin N, Burmester GR, Codreanu C, Conway R, Dougados M, Emery P, Ferraccioli G, Fonseca J, Raza K, Silva-Fernández L, Smolen JS, Skingle D, Szekanecz Z, Kvien TK, van der Helm-van Mil A, van Vollenhoven R. (2017) 2016 update of the EULAR recommendations for the management of early arthritis. Ann Rheum Dis 76:948-959.

Steenbergen HW van, Aletaha D, van de Voorde LJJB, Brouwer E, Codreanu C, Combe B, Fonseca JE, Hetland ML, Humby F, Kvien TK, Niedermann K, Nuño L, Oliver S, Rantapää-Dahlqvist S, Raza K, van Schaardenburg D, Schett G, De Smet L, Szücs G, Vencovský J, Wiland P, de Wit M, Landewé RL, van der Helm-van Mil AHM. (2017) Extended report: EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis. Ann Rheum Dis 2017 76:491-496.

Gonçalves MJ, Mourão AF, Martinho A, Simões O, Melo-Gomes J, Salgado M, Estanqueiro P, Ribeiro C, Brito I, Fonseca JE, Canhão H. (2017) Genetic Screening of Mutations Associated with Fabry Disease in a Nationwide Cohort of Juvenile Idiopathic Arthritis Patients. Front Med (Lausanne) 4:12.

Perpétuo IP, Caetano-Lopes J, Rodrigues AM, Campanilho-Marques R, Ponte C, Canhão H, Ainola M, Fonseca JE. (2017) Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Rheumatoid Arthritis. Biomed Res Int 2017:2690402.

Martins NFE, Seixas MI, Pereira JP, Costa MM, Fonseca JE. (2017) Anti-müllerian hormone and ovarian reserve in systemic lupus erythematosus. Clin Rheumatol 2017 Aug 22. doi: 10.1007/s10067-017-3797-0. [Epub ahead of print]

Fonseca VR, Agua-Doce A, Maceiras AR, Pierson W, Ribeiro F, Romão VC, Pires AR, da Silva SL, Fonseca JE, Sousa AE, Linterman MA, Graca L. (2017) Human blood Tfr cells are indicators of ongoing humoral activity not fully licensed with suppressive function. Sci Immunol. 2017 Aug 11;2(14). pii: eaan1487. doi: 10.1126/sciimmunol.aan1487.

Parker LK, Ponte C, Howell KJ, Ong VH, Denton CP, Schreiber BE. (2017) Clinical features and management of erythromelalgia: long term follow-up of 46 cases. Clin Exp Rheumatol 35: 80-84.

Carvalho PD, Duarte C, Vieira-Sousa E, Cunha-Miranda L, Avila-Ribeiro P, Santos H, Bernardes M, Santos MJ, Cerqueira M, Mateus M, Nero P, Águeda A, Silva JA, Machado P. (2017) Predictors of response to TNF blockers in patients with polyarticular psoriatic arthritis. Acta Reumatol Port 42: 55-65.

2018

Teixeira V, Cordeiro I, Gonçalves MJ, Fonseca JE, Macieira C. Telerheumatology – breaking barriers to access care in Rheumatology. Acta Reumatol Port. 2018 Oct-Dec;43(4):253-255. (IF: 1.105, Citations: 0).

Guerreiro CS, Calado Â, Sousa J, Fonseca JE. Diet, Microbiota, and Gut Permeability-The Unknown Triad in Rheumatoid Arthritis. Front Med (Lausanne). 2018 Dec 14;5:349. doi: 10.3389/fmed.2018.00349. eCollection 2018. (IF: -, Citations: -).

Najm A, Le Goff B, Orr C, Thurlings R, Cañete JD, Humby F, Alivernini S, Manzo A, Just SA, Romão VC, Krenn V, Müller-Ladner U, Addimanda O, Tas SW, Stoenoiu M, Meric de Bellefon L, Durez P, Strand V, Wechalekar MD, Fonseca JE, Lauwerys B, Fearon U, Veale D; EULAR Synovitis Study Group and OMERACT Synovial Tissue Special Interest Group. Standardisation of synovial biopsy analyses in rheumatic diseases: a consensus of the EULAR Synovitis and OMERACT Synovial Tissue Biopsy Groups. Arthritis Res Ther. 2018 Dec 3;20(1):265. doi: 10.1186/s13075-018-1762-1. (IF: 4.269, Citations: 1).

Bergstra SA, Winchow LL, Murphy E, Chopra A, Salomon-Escoto K, Fonseca JE, Allaart CF, Landewé RBM. How to treat patients with rheumatoid arthritis when methotrexate has failed? The use of a multiple propensity score to adjust for confounding by indication in observational studies. Ann Rheum Dis. 2019 Jan;78(1):25-30. doi: 10.1136/annrheumdis-2018-213731. Epub 2018 Oct 16. (IF: 12.350, Citations: 0).

Canet LM, Sánchez-Maldonado JM, Cáliz R, Ramos AR, Lupiañez CB, Canhão H, Martínez-Bueno M4, Escudero A, Segura-Catena J, Sorensen SB, Hetland ML, Soto-Pino MJ, Ferrer MA, García A, Glintborg B, Filipescu I, Pérez-Pampin E, González-Utrilla A, Nevot MÁL, Conesa-Zamora P, Broeder AD, De Vita S, Jacobsen SEH, Collantes-Estevez E, Quartuccio L, Canzian F, Fonseca JE, Coenen MJH, Andersen V, Sainz J. Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients. Pharmacogenomics J. 2019 Feb;19(1):83-96. doi: 10.1038/s41397-018-0057-x. Epub 2018 Oct 5. (IF: 3.812, Citations: 0).

Dekkers JS, Bergstra SA, Chopra A, Tikly M, Fonseca JE, Salomon-Escoto K, Huizinga TWJ, van der Woude D. Autoantibody status is not associated with early treatment response to first-line methotrexate in patients with early rheumatoid arthritis. Rheumatology (Oxford). 2019 Jan 1;58(1):149-153. doi: 10.1093/rheumatology/key263. (IF: 5.245, Citations: 0).

Santos MR, Couto AR, Foroni I, Bettencourt BF, Li Z, Meneses R, Wheeler L, Pereira J, Pimentel-Santos F, Fonseca JE, Alves H, Martinho A, Lima M, Brown MA, Bruges-Armas J. Non-classical human leucocyte antigens in ankylosing spondylitis: possible association with HLA-E and HLA-F. RMD Open. 2018 Jun 28;4(1):e000677. doi: 10.1136/rmdopen-2018-000677. eCollection 2018. (IF: -, Citations: -).

Fonseca JE, Pereira da Silva JA, Bernardes M, Cernadas R, Canas da Silva J, Costa L, Videira T, C Miranda L, Barcelos A, Laires PA, Dezerto R, D Pereira M, Vidal F, Cunha E, Morais A, Martins C, Mesquita R. Effectiveness of a Referral Program for rheumatoid arthritis and axial spondyloarthritis Diagnosis at Primary Care Centers in Portugal – SIARA STUDY. Acta Reumatol Port. 2018 Jan-Mar;43(1):40-51. (IF: 1.105, Citations: 0).

Vidal B, Cascão R, Finnilä MAJ, Lopes IP, Saarakkala S, Zioupos P, Canhão H, Fonseca JE. Early arthritis induces disturbances at bone nanostructural level reflected in decreased tissue hardness in an animal model of arthritis. PLoS One. 2018 Jan 9;13(1):e0190920. doi: 10.1371/journal.pone.0190920. eCollection 2018. (IF: 2.776, Citations: 0).

Vidal B, Cascão R, Finnilä MAJ, Lopes IP, da Glória VG, Saarakkala S, Zioupos P, Canhão H, Fonseca JE. Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model. Rheumatology (Oxford). 2018 Aug 1;57(8):1461-1471. doi: 10.1093/rheumatology/kex258. (IF: 5.245, Citations: 1).

Limper M, Scirè CA, Talarico R, Amoura Z, Avcin T, Basile M, Burmester G, Carli L, Cervera R, Costedoat-Chalumeau N, Doria A, Dörner T, Fonseca JE, Galetti I, Hachulla E, Launay D, Lourenco F, Macieira C, Meroni P, Montecucco CM, Moraes-Fontes MF, Mouthon L, Nalli C, Ramoni V, Tektonidou M, van Laar JM, Bombardieri S, Schneider M, Smith V, Vieira A, Cutolo M, Mosca M, Tincani A. Antiphospholipid syndrome: state of the art on clinical practice guidelines. RMD Open. 2018 Oct 18;4(Suppl 1):e000785. doi: 10.1136/rmdopen-2018-000785. eCollection 2018. (IF: -, Citations: -).

Canhão H, Rodrigues AM, Gregório MJ, Dias SS, Melo Gomes JA, Santos MJ, Faustino A, Costa JA, Allaart C, Gvozdenović E, van der Heijde D, Machado P, Branco JC, Fonseca JE, Silva JA. Common Evaluations of Disease Activity in Rheumatoid Arthritis Reach Discordant Classifications across Different Populations. Front Med (Lausanne). 2018 Mar 8;5:40. doi: 10.3389/fmed.2018.00040. eCollection 2018. (IF: -, Citations: 3).

Fonseca VR, Romão VC, Fonseca JE, Agua-Doce A, Graca L. Reply to the letter: Is the T Follicular Regulatory:Follicular Helper T Cell Ratio in Blood a Biomarker for Ectopic Lymphoid Structure Formation in Sjögren’s Syndrome? Comment on the Article by Fonseca et al. Arthritis Rheumatol. 2018 Aug;70(8):1355-1356. doi: 10.1002/art.40487. Epub 2018 Jun 22. IF: 7.873, Citations: 0).

Tamirou F, Arnaud L, Talarico R, Scirè CA, Alexander T, Amoura Z, Avcin T, Bortoluzzi A, Cervera R, Conti F, Cornet A, Devilliers H, Doria A, Frassi M, Fredi M, Govoni M, Houssiau F, Lladò A, Macieira C, Martin T, Massaro L, Moraes-Fontes MF, Pamfil C, Paolino S, Tani C, Tas SW, Tektonidou M, Tincani A, Van Vollenhoven RF, Bombardieri S, Burmester G, Fonseca JE, Galetti I, Hachulla E, Mueller-Ladner U, Schneider M, Smith V, Cutolo M, Mosca M, Costedoat-Chalumeau N. Systemic lupus erythematosus: state of the art on clinical practice guidelines. RMD Open. 2018 Nov 27;4(2):e000793. doi: 10.1136/rmdopen-2018-000793.(IF: -, Citations: -).

Benjamin C, Carlo Alberto S, Rosaria T, Tobias A, Zahir A, Tadej A, Lorenzo B, Andrea D, Aurelien G, Vera G, Éric H, Thomas K, David L, Gemma L, Pia M, Ulf ML, Simona R, Ana R, Sander W T, van Vollenhoven R F, Ana V, Stefano B, Fonseca JE, Ilaria G, Matthias S, Vanessa S, Maurizio C, Marta M, Rebecca FB. Mixed connective tissue disease: state of the art on clinical practice guidelines. RMD Open. 2018 Oct 18;4(Suppl 1):e000783. doi: 10.1136/rmdopen-2018-000783. (IF: -, Citations: -).

Smith V, Scirè CA, Talarico R, Airo P, Alexander T, Allanore Y, Bruni C, Codullo V, Dalm V, De Vries-Bouwstra J, Della Rossa A, Distler O, Galetti I, Launay D, Lepri G, Mathian A, Mouthon L, Ruaro B, Sulli A, Tincani A, Vandecasteele E, Vanhaecke A, Vanthuyne M, Van den Hoogen F, Van Vollenhoven R, Voskuyl AE, Zanatta E, Bombardieri S, Burmester G, Fonseca FE, Frank C, Hachulla E, Houssiau F, Mueller-Ladner U, Schneider M, van Laar JM, Vieira A, Cutolo M, Mosca M, Matucci-Cerinic M. Systemic sclerosis: state of the art on clinical practice guidelines. RMD Open. 2018 Oct 18;4(Suppl 1):e000782. doi: 10.1136/rmdopen-2018-000782.(IF: -, Citations: -).

Martins, Nádia, MD; Antunes, Ana Patrícia, MD; Macieira, Carla, MD JCR. Neuromyelitis Optica Spectrum Disorder in a Patient with Systemic Lupus Erythematosus. Journal of Clinical Rheumatology February 27, 2018. Apr;14(3):425-7. doi: 10.1177/1352458507084107. (IF: 1.974, Citations: 0).

Seixas, Maria Inês, MD; Marques, Tiago, MD; Ferreira, Cristina, MD; Romeu, José Carlos, MD; Macieira, Carla, MD JCR. Visceral Leishmaniasis Versus Systemic Lupus Erythematosus Flare-Old Axioms Sometimes Stay True Other Times Not. Journal of Clinical Rheumatology: 2018 Sep 21. doi: 10.1097/RHU.0000000000000902. (IF: 1.974, Citations: 0).

Khmelinskii N, Seixas I, Ponte C, Fonseca JE, Macieira C. The added value of a vasculitis clinic in a tertiary referral hospital. Acta Medica Portuguesa. 2018 Nov 30;31(11):614-617. doi: 10.20344/amp.9875. Epub 2018 Nov 30. (IF: 0.581, Citations: 0).

Monti S, Floris A, Ponte C, et al. The use of ultrasound to assess giant cell arteritis: review of the current evidence and practical guide for the rheumatologist. Rheumatology (Oxford). 2018 Feb 1;57(2):227-235. doi: 10.1093/rheumatology/kex173. (IF: 5.245, Citations: 8).

Monti S, Floris A, Ponte CB, et al. The proposed role of ultrasound in the management of giant cell arteritis in routine clinical practice. Rheumatology (Oxford). 2018 Jan 1;57(1):112-119. doi: 10.1093/rheumatology/kex341. (IF: 5.245, Citations: 4).

Dejaco C, Ramiro S, Duftner C, Besson FL, Bley TA, Blockmans D, Brouwer E, Cimmino MA, Clark E, Dasgupta B, Diamantopoulos AP, Direskeneli H, Iagnocco A, Klink T, Neill L, Ponte C, Salvarani C, Slart R, Whitlock M, Schmidt WA. EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice. Ann Rheum Dis. 2018 May;77(5):636-643. doi: 10.1136/annrheumdis-2017-212649. (IF: 12.350, Citations: 19).

Chrysidis S, Duftner C, Dejaco C, Schäfer VS, Ramiro S, Carrara G, Scirè C, Hocevar A, Diamantopoulos AP, Iagnocco A, Mukhtyar C, Ponte C, Naredo E, De Miguel E, Bruyn GA, Warrington KJ, Terslev L, Milchert M, D’Agostino MA, Koster MJ, Rastalsky N, Hanova P, Macchioni P, Kermani TA, Lorenzen T, Døhn UM, Fredberg U, Hartung W, Dasgupta B, Schmidt WA. Definitions and Reliability Assessment of Elementary Ultrasound Lesions in Giant Cell Arteritis: A Study from the OMERACT Large Vessel Vasculitis Ultrasound Working Group RMD Open. 2018 May 17;4(1):e000598. doi: 10.1136/rmdopen-2017-000598. (IF: -, Citations: 4).

Schäfer VS, Chrysidis S, Dejaco C, Duftner C, Iagnocco A, Bruyn GA, Carrara G, D’Agostino MA, De Miguel E, Diamantopoulos AP, Fredberg U, Hartung W, Hocevar A, Juche A, Kermani TA, Koster MJ, Lorenzen T, Macchioni P, Milchert M, Døhn UM, Mukhtyar C, Ponte C, Ramiro S, Scirè CA, Terslev L, Warrington KJ, Dasgupta B, Schmidt WA. Assessing Vasculitis in Giant Cell Arteritis by Ultrasound: Results of an OMERACT Patient-based Agreement and Reliability Exercise. J Rheumatol. 2018 Aug;45(9):1289-1295. doi: 10.3899/jrheum.171428. (IF: 4.475, Citations: 1).

Ponte C, Águeda AF, Luqmani RA. Clinical features and structured clinical evaluation of vasculitis. Best Practice & Research Clinical Rheumatology, 2018 Feb;32(1):31-51; DOI: 10.1016/j.berh.2018.10.001. (IF: 3.198, Citations: 0).

Rednic S*, Damian L*, Tararico R, Scirè CA, Tobias A, Costedoat-Chalumeau N, Launay D, Mathian A, Mattews L, Ponte C, Toniati P, Bombardieri S, Frank C, Schneider M, Smith V, Cutolo M, Mosca M, Arnaud L. Relapsing polychondritis: state of the art on Clinical Practice Guidelines. RMD Open. 2018 Oct 18;4 (Suppl 1):e000788. doi: 10.1136/rmdopen-2018-000788. (IF: -, Citations: -).

Humby F, Romão VC, Manzo A, Filer A, Bugatti S, Vieira-Sousa E, Kelly S, Wechalekar M, Ahmed M, Rocher V, Hands R, Montecucco C, Fonseca J, Pitzalis C. A Multicenter Retrospective Analysis Evaluating Performance of Synovial Biopsy Techniques in Patients With Inflammatory Arthritis: Arthroscopic Versus Ultrasound-Guided Versus Blind Needle Biopsy. Arthritis Rheumatol. 2018 May;70(5):702-710. doi: 10.1002/art.40433. (IF: 7.873, Citations: 0).

Rodrigues AM, Canhão H, Marques A, Ambrósio C, Borges J, Coelho P, Costa L, Fernandes S, Gonçalves I, Gonçalves M, Guerra M, Marques ML, Pimenta S, Pinto P, Sequeira G, Simões E, Teixeira L, Vaz C, Vieira-Sousa E, Vieira R, Alvarenga F, Araújo F, Barcelos A, Barcelos F, Barros R, Bernardes M, Canas da Silva J, Cordeiro A, Costa M, Cunha-Miranda L, Cruz M, Duarte AC, Duarte C, Faustino A, Figueiredo G, Fonseca JE, Furtado C, Gomes J, Lopes C, Mourão AF, Oliveira M, Pimentel-Santos FM, Ribeiro A, Sampaio da Nóvoa T, Santiago M, Silva C, Silva-Dinis A, Sousa S, Tavares-Costa J, Terroso G, Vilar A, Branco JC, Tavares V, Romeu JC, da Silva J. Portuguese recommendations for the prevention, diagnosis and management of primary osteoporosis – 2018 update. Acta Reumatol Port. 2018 Jan-Mar;43(1):10-31. (IF: 1.105, Citations: 1).

Vieira-Sousa E, Canhão H, Alves P, Rodrigues AM, Teixeira F, Tavares-Costa J, Bernardo A, Pimenta S, Pimentel-Santos F, Gomes JL, Aguiar R, Videira T, Pinto P, Catita C, Santos H, Borges J, Sequeira G, Ribeiro C, Teixeira L, Ávila-Ribeiro P, Martins FM, Ribeiro RM, Fonseca JE. The GO-DACT protocol: a multicentre, randomized, double-blind, parallel-group study to compare the efficacy of golimumab in combination with methotrexate (MTX) versus MTX monotherapy. Acta Reumatol Port. 2018 Apr-Jun;43(2):80-92. (IF: 1.105, Citations: 0).

Melo-Gomes JA, Oliveira-Ramos F, Consolaro A, Bovis F, Ruperto N; Paediatric Rheumatology International Trials Organisation (PRINTO). The Portuguese version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR). Rheumatol Int. 2018 Apr;38(Suppl 1):323-329. doi: 10.1007/s00296-018-3967-7.(IF: 1.952, Citations: 0).

Teixeira V, Oliveira-Ramos F, Costa M. Severe and Refractory Polyarteritis Nodosa Associated With CECR1 Mutation and Dramatic Response to Infliximab in Adulthood. J Clin Rheumatol. 2018 Jun 18. doi: 10.1097/RHU.0000000000000839.(IF: 1.974, Citations: 0).

Khmelinskii N, da Silva Dinis J, Teixeira V, Romeu JC. Pseudotumor of the Odontoid Process in Calcium Pyrophosphate Deposition Disease. J Clin Rheumatol. 2018 Mar 7. doi: 10.1097/RHU.0000000000000739. (IF: 1.974, Citations: 0).

Bigotte Vieira M, Dias JM, Romeu JC, Pereira M, Pinto de Abreu C. Persistent knee pain in a patient with systemic lupus erythematosus. Port J Nephrol Hypert 2018; 32(4): 319-323. (IF: -, Citations: -).

Canhao H, Rodrigues AM, Gregório MJ, Dias SS, Melo-Gomes JA, Santos MJ, Faustino A, Costa JA, Allaart C, Gvozdenovic E, van der Heijde D, Machado P, Branco JC, Fonseca JE, da Silva JA. Common evaluation of disease activity in rheumatoid arthritis reach discordant classifications across different populations. Front. Med. 8Mar2018 doi.org/10.3389/fmed.2018.00040. (IF: -, Citations: 2).

Rodrigues AM, Eusébio M, Santos MJ, Gouveia N, Tavares V, Coelho PS, Mendes JM, Branco JC, Canhão H. The burden and under treatment of fragility fractures among senior women. Arch Osteoporos (2018) 13:22; doi.org/10.1007/s11657-018-0430-z. (IF: 2.382, Citations: 1).

Duarte AC, Santos MJ, Cordeiro A. Anti-fibrotic nintedanib – a new opportunity for systemic sclerosis patients. Clin Rheumatol. 2018 Apr;37(4):1123-1127.doi: 10.1007/s10067-017-3867-3. (IF: 2.141, Citations: 1).

Teixeira L, Fonseca C, Sousa S, Vinagre F, Cordeiro A, Gonçalves P, Santos MJ, Canas da Silva J. Safety of Etanercept in the treatment of rheumatic disease patients with Hepatitis C vírus infection. Acta Reumatol Port 2018 Apr-Jun; 43(2) 159-160. (IF: 1.105, Citations: 0).

Khmelinskii N, Regel A, Baraliakos X. The Role of Imaging in Identifying Axial Spondyloarthritis. Front Med (Lausanne) 2018; 5:106. doi: 10.3389/fmed.2018.00106. (IF: -, Citations: -).

Deakin CT*, Campanilho-Marques R*, Simou S, Moraitis E, Wedderburn LR, Pullenayegum E, Pilkington CA; Efficacy and Safety of Cyclophosphamide Treatment in Severe Juvenile Dermatomyositis Shown by Marginal Structural Modeling. Arthritis Rheumatol. 2018 May;70(5):785-793. doi: 10.1002/art.40418. (IF: 7.873, Citations: 3).

Just S, Humby F, Lindegaard H, Bellefon L, Durez P, Vieira-Sousa E, Teixeira RL, Stoenoiu M, Werlinrud J, Rosmark S, Larsen PV, Pratt A, Choy E, Gendi N, Buch M, Edwards CJ, Taylor P, McInnes IB, Fonseca JE, Pitzalis C, Filer A. Patient reported outcomes and safety in patients undergoing synovial biopsy: comparison of ultrasound-guided needle biopsy, ultrasound-guided portal and forceps and arthroscopic-guided synovial biopsy techniques in five centres across Europe. RMD Open. 2018 Oct 26;4(2):e000799. doi: 10.1136/rmdopen-2018-000799. (IF: -, Citations: -).

Geenen R, Overman CL, Christensen R, Åsenlöf P, Capela S, Huisinga KL, Husebø MEP, Köke AJA, Paskins Z, Pitsillidou IA, Savel C, Austin J, Hassett AL, Severijns G, Stoffer-Marx M, Vlaeyen JWS, Fernández-de-Las-Peñas C, Ryan SJ, Bergman S. EULAR recommendations for the health professional’s approach to pain management in inflammatory arthritis and osteoarthritis. Ann Rheum Dis. 2018 Jun;77(6):797-807. doi: 10.1136/annrheumdis-2017-212662. (IF: 12.350, Citations: 4).

Romão VC, Fonseca JE, Agua-Doce A, Graca L. T Follicular Regulatory Cells Are Decreased in Patients with Established Treated Rheumatoid Arthritis With Active Disease: Comment on the Article by Liu et al. Arthritis Rheumatol. 2018 Nov;70(11):1893-1895. doi: 10.1002/art.40586. Epub 2018 Sep 3. (IF: 7.873, Citations: 1).

Romão VC, Talarico R, Scirè CA, Vieira A, Alexander T, Baldini C, Gottenberg JE, Gruner H, Hachulla E, Mouthon L, Orlandi M, Pamfil C, Pineton M, Taglietti M, Toplak N, van Daele P, van Laar Jacob M, Bombardieri S, Schneider M, Smith V, Cutolo M, Mosca M, Mariette X. State of the art on Clinical Practice Guidelines: Sjögren’s Syndrome. RMD Open 2018 Oct 18;4(Suppl 1):e000789. doi: 10.1136/rmdopen-2018-000789. (IF: -, Citations: -).

Leal I, Rodrigues FB, Sousa DC, Romão VC, Duarte GS, Carreño E, Dick AD, Marques-Neves C, Costa J, Fonseca JE. Efficacy and safety of intravitreal anti-tumour necrosis factor drugs in adults with non-infectious uveitis – a systematic review. Acta Ophthalmol 2018 Sep;96(6):e665-e675. doi: 10.1111/aos.13699. (IF: 3.324, Citations: 1)

Fonseca VR, Romão VC, Agua-Doce A, Santos M, López-Presa D, Ferreira AC, Fonseca JE, Graca L. The ratio of blood T follicular regulatory cells to T follicular helper cells marks ectopic lymphoid structure formation while activated follicular helper T cells indicate disease activity in primary Sjögren’s syndrome. Arthritis Rheumatol 2018 May; 70(5):774-784. doi: 10.1002/art.40424. (IF: 7.873, Citations: 10).

Fonseca VR, Romão VC, Agua-Doce A, Fonseca JE, Graca L. Two independent studies show blood follicular T cell subsets allow the stratification of Sjögren’s syndrome patients. Arthritis Rheumatol 2018 Aug;70(8):1355-1356. doi: 10.1002/art.40487. (IF: 7.873, Citations: -).

2019

Polido-Pereira J*, Serra S*, Teixeira F*, Ponte C, Cerqueira M, Cruz M, Araújo F, Barros R, Costa T, Faria D, Lopes C, Madruga-Dias J, Oliveira M, Teixeira RL, Vilar A, Falcão S, Saraiva F, Figueiredo G (*These authors contributed equally to this manuscript). Portuguese recommendations for the use of ultrasound in rheumatology. Acta Reumatol Port. 2019 Jan-Mar;44(1):7-28. (IF: 0.776, Citations: 0).

Martins P, Marques D, Janeiro J, Romeu JC, Ponte C. Tumoral calcinosis in a rheumatoid arthritis patient – a rare case report. Acta Reumatol Port. 2019;44:158-160 [PMID:31455753] (IF: 0.776, Citations: 0).

Guerra M_,Martins P_,Machado AR_,Barreira SC_,Vieira-Sousa E_,Vitorino E_,Romeu JC_,Khmelinskii N.The importance of timely diagnosing tuberculous arthritis – the role of ultrasound-guided biopsy. [Accepted for publication in Journal of Clinical Rheumatology]. (IF: 1.897, Citations: 0).

Martins P, Teixeira V, Saraiva F, Ponte C. The geyser sign: an unusual presentation of a rotator cuff tear. Acta Reumatol Port. 2019 Mar 30. [Epub ahead of print] (IF: 0.776, Citations: 0).

Hellmich B, Agueda A, Monti S, Buttgereit F, de Boysson H, Brouwer E, Cassie R, Cid MC, Dasgupta B, Dejaco C, Hatemi G, Hollinger N, Mahr A, Mollan SP, Mukhtyar C, Ponte C, Salvarani C, Sivakumar R, Tian X, Tomasson G, Turesson C, Schmidt W, Villiger PM, Watts R, Young C, Luqmani RA. 2018 Update of the EULAR recommendations for the management of large vessel vasculitis. Ann Rheum Dis. 2019 Jul 3. pii: annrheumdis-2019-215672. doi: 10.1136/annrheumdis-2019-215672. [Epub ahead of print] (IF: 14.299, Citations: 0).

Gribbons KB, Ponte C, Carette S, Craven A, Cuthbertson D, Hoffman G, Khalidi N, Koening CL, Langford C, Maksimowicz-McKinnon K, McAlear C, Monach P, Moreland L, Pagnoux C, Quinn K, Robson JC, Seo P, Sreih AG, Suppiah R, Warrington KJ, Ytterberg S, Luqmani RA, Watts RA, Merkel PA, Grayson PC. Patterns of Arterial Disease in Takayasu’s Arteritis and Giant Cell Arteritis. Arthritis Care Res (Hoboken). 2019 Aug 23. doi: 10.1002/acr.24055. [Epub ahead of print] (IF: 4.53, Citations: 0).

Monti S, Águeda AF, Luqmani RA, Buttgereit F, Cid M, Dejaco C, Mahr A, Ponte C, Salvarani C, Schmidt WA, Hellmich B. Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis: focus on giant cell arteritis. RMD Open 2019;5:e001003. doi: 10.1136/rmdopen-2019-001003 (IF: 3.47, Citations: 0).

Águeda AF, Monti S, Luqmani RA, Buttgereit F, Cid M, Dejaco C, Mahr A, Ponte C, Salvarani C, Schmidt WA, Hellmich B. Management of Takayasu arteritis: a systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis. RMD Open 2019;5:e001020. doi: 10.1136/rmdopen-2019-001020 (IF: 3.47, Citations: 0).

Ponte C, Martins-Martinho J, Luqmani RA. Diagnosis of Giant Cell Arteritis. Rheumatology (Oxford) 2019 (Accepted) (IF: 5.145, Citations: 0).

Monti S, Ponte C, Pereira C, Manzoni F, Klersy C, Rumi F, Carrara G, Hutchings A, Schmidt WA, Dasgupta B, Caporali R, Montecucco C, Luqmani RA. The Impact Of Disease Extent And Severity Detected By Quantitative Ultrasound Analysis In The Diagnosis And Outcome Of Giant Cell Arteritis: Results From The Temporal Artery Biopsy Versus Ultrasound (Tabul) Study And Validation In An Independent Cohort. Rheumatology (Oxford) 2019 (Accepted) (IF: 5.145, Citations: 0).

Gribbons KB, Ponte C, Craven A, Robson JC, Suppiah R, Luqmani RA, Watts RA, Merkel PA, Grayson PC. Diagnostic Assessment Strategies and Disease Subsets in Giant Cell Arteritis: An International Observational Cohort. Arthritis & Rheum 2019 (Accepted) (IF: 9.002, Citations: 0).

Duarte AC, Cordeiro A, Fernandes BM, Bernardes M, Martins P, Cordeiro I, Santiago T, Seixas MI, Ribeiro AR, Santos MJ. Rituximab in connective tissue disease-associated interstitial lung disease. Clin Rheumatol. 2019 Jul;38(7):2001-2009. doi: 10.1007/s10067-019-04557-7. (IF: 2.293, Citations: 0).

Gomes JL, Sepriano A, Eusébio M, Serra S, Fonseca JE, Saavedra MJ, Cunha-Miranda L, Silva C, Bernardes M, Rosa-Gonçalves D, Costa J, Castelão W, Branco JC, Santos MJ. Predictors and causes of first-line biologic agent discontinuation in rheumatoid arthritis: data from Reuma.pt. Acta Reumatol Port. 2019 Jan-Mar;44(1):57-64. (IF: 0.776, Citations: 0).

Santos-Faria D, Tavares-Costa J, Eusébio M, Leite Silva J, Ramos Rodrigues J, Sousa Neves J, Duarte AC, Lopes C, Valido A, Dinis J, Freitas J, Santiago M, Ferreira R, Ganhão S, Miranda L, Peixoto D, Teixeira F, Alcino S, Afonso C, Santos MJ. Tocilizumab and rituximab have similar effectiveness and are both superior to a second tumour necrosis factor inhibitor in rheumatoid arthritis patients who discontinued a first TNF inhibitor. Acta Reumat Port 2019 Apr-Jun;44(2):103-113 (IF: 0.776, Citations: 0).

Luís M, Brites A, Duarte A, Teixeira V, Freitas R, Oliveira-Ramos F, Macieira C, Santos M, Inês L. How to diagnose lupus enteritis early? Lessons learned from a multicenter case series. Acta Reumat Port 2019 Apr-Jun;44(2):145-150. (IF: 0.776, Citations: 0).

Romão VC, Polido-Pereira J, Barros R, Luís R, Vidal B, Vieira-Sousa E, Vitorino E, Humby F, Kelly S, Pitzalis C, Saraiva F, Fonseca JE. “Efficacy, safety and sample quality of ultrasound-guided synovial needle biopsy in clinical practice and research: a prospective observational study”. Arthritis Care Res (Hoboken). 2019 Aug 17. doi: 10.1002/acr.24050. (IF: 4.53, Citations: 0).

Meyer A, Scirè CA, Talarico R, Alexander T, Amoura Z, Avcin T, Barsotti S, Beretta L, Blagojevic J, Burmester G, Cavazzana I, Cherrin P, Damian L, Doria A, Fonseca JE, Furini F, Galetti I, Houssiau F, Krieg T, Maddalena L, Launay D, Campanilho-Marques R, Martin T, Matucci-Cerinic M, Moinzadeh P, Montecucco C, Moraes-Fontes MF, Mouthon L, Neri R, Paolino S, Piette Y, Rednic S, Tamirou F, Tincani A, Toplak N, Bombardieri S, Hachulla E, Mueller-Ladner U, Schneider M, Smith V, Vieira A, Cutolo M, Mosca M, Cavagna L. Idiopathic inflammatory myopathies: state of the art on clinical practice guidelines [corrected].RMD Open. 2019 Feb 26;4(Suppl 1):e000784. doi: 10.1136/rmdopen-2018-000784. (IF: 3.47, Citations: 3).

Martins P; Barreira SC; Melo AT; Campanilho-Marques R; Costa-Reis P; Fonseca JE; Oliveira-Ramos F. Transition in a Paediatric Rheumatology Unit – experience from a tertiary unit. Acta Reumatológica Portuguesa. Online First: 2019-11-15. (IF: 0.776, Citations: 0).

Macieira C, Cunha-Miranda L, Nero P, Laires P, Bogas M, Farinha S, Freitas I, Lucas P, Sousa J, Narciso L, Mateus E, Canas da Silva J, Fonseca JE, Study Group RS Rheuma SPACE – Standard Practice Aiming Clinical Excellence: description of the methodological approach. Acta Reumatol Port. 2019 Sep 8. [Epub ahead of print] (IF: 0.776, Citations: 0).

Antunes M, Scirè CA, Talarico R, Alexander T, Avcin T, Belocchi C, Doria A, Franceschini F, Galetti I, Govoni M, Hachulla E, Launay D, Lepri G, Macieira C, Matucci-Cerinic M, Montecucco CM, Moraes-Fontes MF, Mouthon L, Paolino S, Ramoni V, Tani C, Tas SW, Tincani A, Van Vollenhoven R, Zen M, Fonseca J, Bombardieri S, Fonseca JE, Schneider M, Smith V, Cutolo M, Mosca M, Beretta L. ”Undifferentiated connective tissue disease: state of the art on clinical practice guidelines”. RMD Open. 2019 Feb 26;4(Suppl 1):e000786. doi: 10.1136/rmdopen-2018-000786. eCollection 2018. Review. (IF: 3.47, Citations: 1).

Martins N, Antunes AP, Macieira C. “Neuromyelitis Optica Spectrum Disorder in a Patient With Systemic Lupus Erythematosus”. J Clin Rheumatol. 2019 Jun;25(4):38-40. doi: 10.1097/RHU. 0000000000000 718. No abstract available. (IF: 2.293, Citations: 0).

Amaro D, Carreño E, Steeples LR, Oliveira-Ramos F, Marques-Neves C, Leal I. “Tubulointerstitial nephritis and uveitis (TINU) syndrome: a review”. Br J Ophthalmol. 2019 Nov 12. pii: bjophthalmol-2019-314926. doi: 10.1136/bjophthalmol-2019-314926. (IF: 1.580, Citations: 0).

Valido A, Cordeiro I. Calcinosis in Systemic Sclerosis. N Engl J Med. 2019 Oct 24;381(17):1663. doi: 10.1056/NEJMicm1901830. (IF: 70.670, Citations: 0).

Geenen R, Overman CL, Christensen R, Åsenlöf P, Capela S, Huisinga KL, Husebø MEP, Köke AJA ,Paskins Z, Pitsillidou IA, Savel C, Austin J, Hassett AL, Severijns G, Stoffer-Marx M, Vlaeyen JWS, Fernández-de-Las-Peñas C, Ryan SJ, Bergman S. “EULAR recommendations for the health professional’s approach to painmanagement in inflammatory arthitis and osteoartritis. Ann Rheum Dis. 2018 Jun;77(6):797-807. doi: 10.1136/annrheumdis-2017-212662. Epub 2018 May 3.

Ana Valido, Carolina Lago Crespo, Fernando Santos Pimentel. Muscle evaluation in axial spondyloarthritis – The evidence for Sarcopenia. Front. Med 6:2019. DOI: 10.3389/fmed.2019.00219 (IF: 3.113, Citations: 0).

Martins P, Fonseca JE. How to investigate: Pre-clinical rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2019 Oct 15:101438. doi: 10.1016/j.berh.2019.101438. (IF: 2.293, Citations: 0).

Teixeira V, Mohammad AJ, Jones RB, Smith R, Jayne D. Efficacy and safety of rituximab in the treatment of eosinophilic granulomatosis with polyangiitis. RMD Open. 2019 Jun 5;5(1):e000905. doi: 10.1136/rmdopen-2019-000905. eCollection 2019. (IF: 3.47, Citations: 3).

Teixeira V, Barreira S, Valido A, Macieira C, Fonseca JE. Outcomes of rheumatic patients referred from Portuguese speaking African countries for medical evaluation in Portugal. Acta Reumatol Port. 2019 Jul 22. (IF: 0.776, Citations: 0).

Pereira E Silva R, Romão VC, Neves M, Garcia R, Oliveira S, Brites J, Ramos FO, Canhão H, Palma Dos Reis J, Pereira da Silva JA, Lopes T. Overactive bladder symptom bother and health-related quality of life in patients with systemic lupus erythematosus and primary Sjögren syndrome. Lupus. 2019 Jan;28(1):27-33. doi: 10.1177/0961203318811605. Epub 2018 Nov 12. (IF: 2.924, Citations: 0).

Leal IC, Brogueira Rodrigues F, Sousa DC, Duarte G, Romão VC, Neves CM, Costa J, Fonseca JE. Anti-TNF Drugs for Chronic Uveitis in Adults—A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Med. 2019;6:104. doi.org/10.3389/fmed.2019.00104 (IF: 3.113, Citations: 0).

Romão VC, Fonseca JE. Major challenges in Rheumatology: will we ever treat smarter, instead of just harder? Front Med (Lausanne) 2019;6:144. 10.3389/fmed.2019.00144 (IF: 3.113, Citations: 1).

Ramos-Casals M, Brito-Zerón P, Bombardieri S, Bootsma H, De Vita S, Dörner T, Fisher BA, Gottenberg JE, Hernandez-Molina G, Kocher A, Kostov B, Kruize AA, Mandl T, Ng WF, Retamozo S, Seror R, Shoenfeld Y, Sisó-Almirall A, Tzioufas AG, Vitali C, Bowman S, Mariette X; EULAR-Sjögren Syndrome Task Force Group. EULAR recommendations for the management of Sjögren’s syndrome with topical and systemic therapies. Ann Rheum Dis. 2019 Oct 31. pii: annrheumdis-2019-216114. doi: 10.1136/annrheumdis-2019-216114. [Epub ahead of print]. (IF: 14.299, Citations: 0).

Miltenberger-Miltenyi, G, Cruz-Machado, AR, Saville, J, Conceição, VA, Calado, A, Lopes, I, Fuller, M, Fonseca, JE (2019) Increased monohexosylceramide levels in the serum of established rheumatoid arthritis patients, Rheumatology, kez545, https://doi.org/10.1093/rheumatology/kez545 (IF: 5.145, Citations: 0).

Polido-Pereira J. Ultrasound-Guided Biopsies: Medium and Large Joints. Front Med (Lausanne). 2019 May 21;6:95. doi: 10.3389/fmed.2019.00095. eCollection 2019. Review. (IF: 3.113, Citations: 0).

Rodrigues AM, Eusébio M, Rodrigues AB, Caetano-Lopes J, Lopes IP, Lopes A, Mendes JM, Coelho PS, Fonseca JE, Branco JC, Canhão H. Low serum levels of DKK2 predict incident low-impact fracture in older women. JBMR Plus. 2019 Mar 28;3(7):e10179. doi: 10.1002/jbm4.10179. eCollection 2019 Jul. (IF: 5.711, Citations: 0).

Sanmarti R, Veale DJ, Martin-Mola E, Escudero-Contreras A, González C, Ercole L, Alonso R, Fonseca JE; ToSpace Study group. Reducing or maintaining the dose of subcutaneous tocilizumab in patients with rheumatoid arthritis in clinical remission: a randomized, open-label trial. Arthritis Rheumatol. 2019 Apr 5. doi: 10.1002/art.40905. (IF: 9.002, Citations: 1).

Sánchez-Maldonado JM, Cáliz R, Canet L, Horst RT, Bakker O, den Broeder AA, Martínez-Bueno M, Canhão H, Rodríguez-Ramos A, Lupiañez CB, Soto-Pino MJ, García A, Pérez-Pampin E, González-Utrilla A, Escudero A, Segura-Catena J, Netea-Maier RT, Ferrer MÁ, Collantes-Estevez E, López Nevot MÁ, Li Y, Jurado M, Fonseca JE, Netea MG, Coenen MJH, Sainz J. steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: results from the repair consortium. Sci Rep. 2019 Oct 15;9(1):14812. doi: 10.1038/s41598-019-51255-0. (IF: 4.525, Citations: 0).

Araújo FC, Gonçalves J, Fonseca JE. Biosimilars in Rheumatology. Pharmacol Res. 2019 Sep 27:104467. doi: 10.1016/j.phrs.2019.104467. [Epub ahead of print] Review. (IF: 5.574, Citations: 0).

Antunes M, Scirè CA, Talarico R, Alexander T, Avcin T, Belocchi C, Doria A, Franceschini F, Galetti I, Govoni M, Hachulla E, Launay D, Lepri G, Macieira C, Matucci-Cerinic M, Montecucco CM, Moraes-Fontes MF, Mouthon L, Paolino S, Ramoni V, Tani C, Tas SW, Tincani A, Van Vollenhoven R, Zen M, Fonseca J, Bombardieri S, Fonseca JE, Schneider M, Smith V, Cutolo M, Mosca M, Beretta L. Undifferentiated connective tissue disease: state of the art on clinical practice guidelines. RMD Open. 2019 Feb 26;4 (Suppl 1):e000786. doi: 10.1136/rmdopen-2018-000786. eCollection 2018. (IF: 3.47, Citations: 1).

Rocha FAC, Girão VCC, Nunes RM, Pinto ACMD, Vidal B, Fonseca JE. Cell sources of inflammatory mediators present in bone marrow areas inside the meniscus. PLoS One. 2019 Dec 20;14(12):e0226986. doi: 10.1371/journal.pone.0226986. eCollection 2019.(IF: 2.776, Citations: 1).

Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC- R4RA investigators. B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure. Arthritis Rheumatol. 2019 Nov 29. doi: 10.1002/art.41184. [Epub ahead of print] (IF: 9.002, Citations: 1).

Valido A, Silva-Dinis J, Saavedra MJ, Iria I, Gonçalves J, Lopes JP, Fonseca JE. Efficacy, immunogenicity and cost analysis of a systematic switch from originator infliximab to biosimilar CT-P13 of all patients with inflammatory arthritis from a single center. Acta Reumatol Port. 2019 Nov 22. (IF: 0.776, Citations: 0).

Martins N, Polido-Pereira J, Caneira M, Fonseca JE. “Treatment of Persistent Cutaneous Atrophy After Corticosteroid Injection With Fat Graft”. Reumatol Clin. 2019 Nov – Dec;15(6):e122-e124. doi: 10.1016/j.reuma.2017.09.002. Epub 2017 Dec 8. (IF: 1.050, Citations: 1).

2020

Borrega R, Araújo C, Aguiam N, Magro F, Fonseca JE, Danese S, Lopes J, Goncalves J. Systematic Review and Principal Components Analysis of the Immunogenicity of Adalimumab. BioDrugs. 2021 Jan;35(1):35-45. doi: 10.1007/s40259-020-00458-3. (IF: 5.313, Citations: 0).

Talarico R, Aguilera S, Alexander T, Amoura Z, Antunes AM, Arnaud L, Avcin T, Beretta L, Bombardieri S, Burmester GR, Cannizzo S, Cavagna L, Chaigne B, Cornet A, Costedoat-Chalumeau N, Doria A, Ferraris A, Fischer-Betz R, Fonseca JE, Frank C, Gaglioti A, Galetti I, Grunert J, Guimarães V, Hachulla E, Houssiau F, Iaccarino L, Krieg T, Limper M, Malfait F, Mariette X, Marinello D, Martin T, Matthews L, Matucci-Cerinic M, Meyer A, Montecucco C, Mouthon L, Müller-Ladner U, Rednic S, Romão VC, Schneider M, Smith V, Sulli A, Tamirou F, Taruscio D, Taulaigo AV, Terol E, Tincani A, Ticciati S, Turchetti G, van Hagen PM, van Laar JM, Vieira A, de Vries-Bouwstra JK, Cutolo M, Mosca M. The impact of COVID-19 on rare and complex connective tissue diseases: the experience of ERN ReCONNET. Nat Rev Rheumatol. 2021 Jan 6:1-8. doi: 10.1038/s41584-020-00565-z. (IF: 16.625, Citations: 0).

Sánchez-Maldonado JM, Campa D, Springer J, Badiola J, Niazi Y, Moñiz-Díez A, Hernández-Mohedo F, González-Sierra P, Ter Horst R, Macauda A, Brezina S, Cunha C, Lackner M, López-Nevot MA, Fianchi L, Pagano L, López-Fernández E, Potenza L, Luppi M, Moratalla L, Rodríguez-Sevilla JJ, Fonseca JE, Tormo M, Solano C, Clavero E, Romero A, Li Y, Lass-Flörl C, Einsele H, Vazquez L, Loeffler J, Hemminki K, Carvalho A, Netea MG, Gsur A, Dumontet C, Canzian F, Försti A, Jurado M, Sainz J. Host immune genetic variations influence the risk of developing acute myeloid leukaemia: results from the NuCLEAR consortium. Blood Cancer J. 2020 Jul 16;10(7):75. doi: 10.1038/s41408-020-00341-y. (IF: 8.023, Citations: 0).

Romão VC, Cruz-Machado AR, Fonseca JE. No evidence so far on the protective effect of hydroxychloroquine to prevent COVID-19: comment by Joob and Wiwanitkit. Ann Rheum Dis. 2021 Feb;80(2):e22. doi: 10.1136/ annrheu mdis-2020-217665. Epub 2020 May 13. (IF: 16.102, Citations: 0).

Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A, Hands RE, Giorli G, Frias B, Thorborn G, Jaworska E, John C, Goldmann K, Lewis MJ, Manzo A, Bombardieri M, Pitzalis C; PEAC-R4RA Investigators. B Cell Synovitis and Clinical Phenotypes in Rheumatoid Arthritis: Relationship to Disease Stages and Drug Exposure. Arthritis Rheumatol. 2020 May;72(5):714-725. doi: 10.1002/art.41184. Epub 2020 Mar

(IF: 9.586, Citations: 5).

Castro Rocha FA, Duarte-Monteiro AM, Henrique da Mota LM, Matias Dinelly Pinto AC, Fonseca JE. Microbes, helminths, and rheumatic diseases. Best Pract Res Clin Rheumatol. 2020 Aug;34(4):101528. doi: 10.1016/j.berh.2020.101528. Epub 2020 May 7. (IF: 2.727, Citations: 0).

Romão VC, Cordeiro I, Macieira C, Oliveira-Ramos F, Romeu JC, Rosa CM, Saavedra MJ, Saraiva F, Vieira-Sousa E, Fonseca JE. Rheumatology practice amidst the COVID-19 pandemic: a pragmatic view. RMD Open. 2020 Jun;6(2):e001314. doi: 10.1136/rmdopen-2020-001314. (IF: 3.44, Citations: 2).

Carvalho PD, Ruyssen-Witrand A, Fonseca JE, Marreiros A, Machado PM. Determining factors related to impaired spinal and hip mobility in patients with axial spondyloarthritis: longitudinal results from the DESIR cohort. RMD Open. 2020 Oct;6(3):e001356. doi: 10.1136/rmdopen-2020-001356. (IF: 3.44, Citations: 0).

Manuel Sánchez-Maldonado J, Martínez-Bueno M, Canhão H, Ter Horst R, Muñoz-Peña S, Moñiz-Díez A, Rodríguez-Ramos A, Escudero A, Sorensen SB, Hetland ML, Ferrer MA, Glintborg B, Filipescu I, Pérez-Pampin E, Conesa-Zamora P, García A, den Broeder A, De Vita S, Hove Jacobsen SE, Collantes E, Quartuccio L, Netea MG, Li Y, Fonseca JE, Jurado M, López-Nevot MÁ, Coenen MJH, Andersen V, Cáliz R, Sainz J. NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium. Sci Rep (2020) Mar 9;10(1):4316. doi: 10.1038/s41598-020-61331-5. (IF: 3.998, Citations: 1).

Freitas R, Godinho F, Madeira N, Fernandes BM, Costa F, Santiago B , Neto A, Azevedo S, Couto M, Sequeira G, Dias JM, Bernardes M, Cunha-Miranda L, Polido Pereira J, Fonseca JE, Santos MJ. Safety and effectiveness of biologic disease-modifying antirheumatic drugs in older patients with rheumatoid arthritis: a prospective cohort study. Drugs & Ageing 2020 Dec;37(12):899-907. doi: 10.1007/s40266-020-00801-x. (IF: 2.824, Citations:0).

Romão VC, Polido-Pereira J, Barros R, Luís R, Vidal B, Vieira-Sousa E, Vitorino E, Humby F, Kelly S, Pitzalis C, Saraiva F, Fonseca JE. Efficacy, safety and sample quality of ultrasound-guided synovial needle biopsy in clinical practice and research: a prospective observational study. Arthritis Care Res (Hoboken). 2020;72(10):1497-1505. (IF: 4.056, Citations: 1).

Valido A, Silva-Dinis J, Cruz-Machado AR, Gonçalves MJ, Romão VC, Saavedra MJ, Fonseca JE. Loss to follow-up in registries of rheumatic patients treated with biologics: a potential information bias in assessing pharmacovigilance and efficacy outcomes. Acta Reumatol Port 2019;44:281-87.

(IF: 1.183, Citations: 1).

Romão VC, Humby F, Kelly S, Di Cicco M, Mahto A, Lazarou I, Hands R, Rocher-Ros V, van der Heijde D, Fonseca JE, Pitzalis C. Treatment-resistant synovitis and radiographic progression are increased in elderly-onset rheumatoid arthritis patients: findings from a prospective observational longitudinal early arthritis cohort study. Semin Arthritis Rheum 2020;50(4):735-743. (IF: 4.751, Citations:0).

Romão VC, Cruz-Machado AR, Fonseca JE. No evidence so far on the protective effect of hydroxychloroquine to prevent COVID-19: response to the comment by Joob and Wiwanitkit. Ann Rheum Dis 2020; annrheumdis-2020-217665. (IF: 16.101, Citations:0).

Romão VC, Cruz-Machado AR, Fonseca JE. Mounting data indicate that antimalarials do not prevent mild or severe COVID-19 in rheumatic patients. Response to: ‘The role of antimalarials in COVID-19: observational data from a cohort of rheumatic patients’ by Favalli et al. Ann Rheum Dis 2020; annrheumdis-2020-218175. (IF: 16.101, Citations:0).

Cascão R, Vidal B, Carvalho T, Romão VC, Pascoal-Lopes I, Gonçalves J, Ferreira-Moita L, Fonseca JE. Celastrol efficacy by oral administration in the adjuvant-induced arthritis model. Front Med (Lausanne) 2020;7:455. (IF: 3.9, Citations:0).

Romão VC, Oliveira-Ramos F, Cruz-Machado AR, Martins P, Barreira S, Silva-Dinis J, Mendonça-Galaio L, Proença H, Melo Cristino J, Sacadura-Leite E, Khmelinskii N, Romeu JC, Fonseca JE and the CHULN Rheumatology Department. A COVID-19 outbreak in a rheumatology department upon the early days of the pandemic. Front Med (Lausanne) 2020;7:576162.

(IF: 3.9, Citations:0).

Romão VC, Fonseca JE, Pitzalis C. Elderly-onset rheumatoid arthritis is a unique disease subset associated with poor overall outcomes: Response to the letter by Haroon and Ayamer. 2020 Dec 18; S0049-0172(20)30292-4. doi: 10.1016/j.semarthrit.2020.09.015. Online ahead of print. (IF: 4.751, Citations:0).

Rita A. Moura, João E. Fonseca (2021). JAK inhibitors and modulation of B cell immune responses in Rheumatoid Arthritis. Frontiers in Medicine, Rheumatology. Review (accepted for publication in December 2020). (IF: 3.9, Citations:0).

Cruz-Machado AR, Rodrigues-Manica S, Silva JL, Alho I, Coelho C, Duarte J, Florêncio C, Pimentel-Santos FM, Tavares-Costa J, Vieira-Sousa E. (2020). Effect of biologic disease-modifying anti-rheumatic drugs targeting remission in axial spondyloarthritis: systematic review and meta-analysis. Rheumatology, 59(11), 3158-3171. (IF: 5.606, Citations:0).

Miltenberger-Miltenyi G, Cruz-Machado AR, Saville J, Conceição VA, Calado Â, Lopes I, Fuller M, Fonseca JE (2020). Increased monohexosylceramide levels in the serum of established rheumatoid arthritis patients. Rheumatology (Oxford), 1;59(8):2085-2089. (IF: 5.606, Citations:0).

Vieira-Sousa E, Eusébio M, Ávila-Ribeiro P, Khmelinskii N, Cruz-Machado R, Rocha TM, Bernardes M, Santos-Faria D, Silva JL, Santos H, Miguel C, Carvalho P, Costa T, Duarte AC, Meirinhos T, Nero P, Fonseca JE, Santos MJ (2020). Real-world Longterm Effectiveness of Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis Patients from the Rheumatic Diseases Portuguese Register. J Rheumatol, 1;47(5):690-700. (IF: 3.35, Citations:0).

Raquel Campanilho-Marques, Claire T. Deakin, Stefania Simou, Charalampia Papadopoulou, Lucy R. Wedderburn, Clarissa A. Pilkington and for the Juvenile Dermatomyositis Research Group (JDRG). Retrospective analysis of infliximab and adalimumab treatment in a large cohort of juvenile dermatomyositis patients. Arthritis Research & Therapy (2020) 22:79. https://doi.org/10.1186/s13075-020-02164-5. (IF: 4.103, Citations:0).

Kvien TK, Balsa A, Betteridge N, Buch MH, Durez P, Favalli EG, Favier G, Gabay C, Geenen R, Gouni-Berthold I, van den Hoogen F, Kent A, Klareskog L, Ostergaard M, Pavelka K, Polido Pereira J, Semb AG, Sköld M, Dougados M. Considerations for improving quality of care of patients with rheumatoid arthritis and associated comorbidities. RMD Open. 2020 Jul;6(2):e001211. doi: 10.1136/rmdopen-2020-001211. PMID: 32683326; PMCID: PMC7722279. (IF: 3.44, Citations:0).

Silva-Dinis J, Valido A, Polido-Pereira J, Khmelinskii N. Schwannomas Mimicking Rheumatologic Conditions. Reumatol Clin. 2020 Jul 7:S1699-258X(20)30018-8. English, Spanish. doi: 10.1016/j.reuma.2020.01.004. Epub ahead of print. PMID: 32651117. (IF: 2.394, Citations:0).

Romão VC, Polido-Pereira J, Barros R, Luís R, Vidal B, Vieira-Sousa E, Vitorino E, Humby F, Kelly S, Pitzalis C, Saraiva F, Fonseca JE. Efficacy, Safety, and Sample Quality of Ultrasound-Guided Synovial Needle Biopsy in Clinical Practice and Research: A Prospective Observational Study. Arthritis Care Res (Hoboken). 2020 Oct;72(10):1497-1505. doi: 10.1002/acr.24050. PMID: 31421034. (IF: 4.056, Citations:1).

Teixeira V, Oliveira-Ramos F, Costa M. Severe and Refractory Polyarteritis Nodosa Associated With CECR1 Mutation and Dramatic Response to Infliximab in Adulthood. J Clin Rheumatol. 2020 Apr;26(3):e66-e69. doi: 10.1097/RHU.0000000000000839. PMID: 29916967. (IF: 2.36, Citations:1)

Travessa AM, Díaz-González F, Mirco T, Oliveira-Ramos F, Parrón-Pajares M, Heath KE, Sousa AB. Spondyloepiphyseal dysplasia type Stanescu: Expanding the clinical and molecular spectrum of a very rare type II collagenopathy. Am J Med Genet A. 2020 Nov;182(11):2715-2721. doi: 10.1002/ajmg.a.61817. Epub 2020 Aug 28. PMID: 32856782. (IF: 2.125, Citations:0).

Amaro D, Carreño E, Steeples LR, Oliveira-Ramos F, Marques-Neves C, Leal I. Tubulointerstitial nephritis and uveitis (TINU) syndrome: a review. Br J Ophthalmol. 2020 Jun;104(6):742-747. doi: 10.1136/bjophthalmol-2019-314926. Epub 2019 Nov 12. PMID: 31719109. (IF: 3.806 Citations:2).

Melo AT, Campanilho-Marques R, Fonseca JE. Golimumab (anti-TNF monoclonal antibody): where we stand today – Hum Vaccin Immunother. 2020 Dec 28:1-13. doi: 10.1080/21645515.2020.1836919. (IF: 2.619 Citations:0).

Rocha FAC, Duarte-Monteiro AM, da Mota LMH, Pinto ACMD, Fonseca JE (2020). Microbes, Helminths and Rheumatic Diseases. Best Practice & Research Clinical Rheumatology 34 (4). Review (IF:3.016, Citations: 1).

Vasco C Romão, Inês Cordeiro, Carla Macieira, Filipa Oliveira-Ramos, José Carlos Romeu, Carlos Miranda Rosa, Maria João Saavedra, Fernando Saraiva, Elsa Vieira-Sousa, João Eurico Fonseca. Rheumatology practice amidst the COVID-19 pandemic: a pragmatic view. RMD open. https: //doi.org/10.1136/rmdopen-2020-001314. (IF: 3.44, Citations: 2).

Grayson PC, Ponte C, Suppiah R, Robson JC, Craven A, Judge A, Khalid S, Hutchings, Luqmani RA, Watts RA, Merkel PA. 2020 American College of Rheumatology / European League Against Rheumatism Classification Criteria for Eosinohilic Granulomatosis with Polyangiitis. Arthritis Rheumatol. 2020 (accepted, in press) (IF: 9.586; Citations: 0)

Robson JC, Grayson PC, Ponte C, Suppiah R, Craven A, Judge A, Khalid S, Hutchings, Watts RA, Merkel PA, Luqmani RA. 2020 American College of Rheumatology / European League Against Rheumatism Classification Criteria for Granulomatosis with Polyangiitis. Arthritis Rheumatol. 2020 (accepted, in press) (IF: 9.586; Citations: 0)

Suppiah R, Robson JC, Grayson PC, Ponte C, Craven A, Khalid S, Judge A, Hutchings A, Merkel PA, Luqmani RA, Watts RA. 2020 American College of Rheumatology / European League Against Rheumatism Classification Criteria for Microscopic Polyangiitis. Arthritis Rheumatol. 2020 (accepted, in press) (IF: 9.586; Citations: 0)

Putman MS, Gribbons KB, Ponte C, Robson JC, Suppiah R, Craven A, Watts RA, Luqmani RA, Merkel PA, Archer AM, Grayson PC. Clinicopathologic Associations in a Large International Cohort of Patients with Giant Cell Arteritis. Arthritis Care Res (Hoboken) 2020 Dec 18. doi: 10.1002/acr.24540. Online ahead of print. (IF: 4.056; Citations: 0)

Kaushik M, Ponte C, Mollan SP. Current advances in Giant Cell Arteritis. Current Opinion Neurology 2020 Nov 20. doi: 10.1097/WCO.0000000000000889. Online ahead of print. (IF: 4.207; Citations: 0)

Barreira SC, Melo AT, Ponte C, Khmelinskii N. Macaroni sign and carotid occlusion in Takayasu’s arteritis. Rheumatology (Oxford) 2020 Nov 3; keaa520. doi: 10.1093/rheumatology/keaa520. Online ahead of print. (IF: 5.606; Citations: 0)

Martins P, Valido A, Melo AT, Santareno S, Sousa R, Inácio JR, Oliveira-Ramos F, Ponte C, Romeu JC. Posterior reversible encephalopathy syndrome and digital gangrene in a patient with granulomatosis with polyangiitis – a rare case report. Acta Reumatol Port. 2020; 45:65-68. (IF: 1.183; Citations: 0)

Martins P, Teixeira V, Teixeira F, Canastro M, Palha A, Fonseca JE, Ponte C. Giant cell arteritis with normal inflammatory markers: case report and review of the literature. Clinical Rheumatology 2020. DOI: 10.1007/s10067-020-05116-1 (IF: 2.394; Citations:1)

Ponte C, Serafim AS, Monti S, Fernandes E, Lee E, Singh S, Piper J, Hutchings A, McNally E, Diamantopoulos AP, Dasgupta B, Schmidt WA, Luqmani RA. Early variation of ultrasound halo sign with treatment and relation with clinical features in patients with giant cell arteritis. Rheumatology (Oxford). 2020 May 11. pii: keaa196. doi: 10.1093/rheumatology/keaa196. [Epub ahead of print] (IF: 5.606; Citations: 4)

Ponte C, Martins-Martinho J, Luqmani RA. Diagnosis of giant cell arteritis. Rheumatology (Oxford). 2020; 59(Supplement_3): iii5-iii16. (IF: 5.606; Citations: 0)

Ponte C, Khmelinskii N, Teixeira V, Luz K, Peixoto D, Rodrigues M, Luís M, Teixeira L, Sousa S, Madeira N, Aleixo JA, Pedrosa T, Serra S, Campanilho-Marques R, Castelão W, Cordeiro A, Cordeiro I, Fernandes S, Macieira C, Madureira P, Malcata A, Vieira R, Martins F, Sequeira G, Branco JC, Costa L, Vaz Patto J, Canas da Silva J, Pereira da Silva JA, Afonso C, Canhão H, Santos MJ, Luqmani RA, Fonseca JE. Reuma.pt/vasculitis – the Portuguese vasculitis registry. Orphanet J Rare Dis. 2020; 15:110-122. (IF: 3.523; Citations: 0)

Gribbons KB, Ponte C, Craven A, Robson JC, Suppiah R, Luqmani R, Watts R, Merkel PA, Grayson PC. Diagnostic Assessment Strategies and Disease Subsets in Giant Cell Arteritis: Data from an International Observational Cohort. Arthritis Rheumatol. 2020; 72:667-676. (IF: 9.586; Citations: 3)

Hellmich B, Agueda A, Monti S, Buttgereit F, de Boysson H, Brouwer E, Cassie R, Cid MC, Dasgupta B, Dejaco C, Hatemi G, Hollinger N, Mahr A, Mollan SP, Mukhtyar C, Ponte C, Salvarani C, Sivakumar R, Tian X, Tomasson G, Turesson C, Schmidt W, Villiger PM, Watts R, Young C, Luqmani RA. 2018 Update of the EULAR recommendations for the management of large vessel vasculitis. Annals of the Rheumatic Diseases 2020; 79:19-30. (IF: 16,102; Citations: 78)

Monti S, Ponte C, Pereira C, Manzoni F, Klersy C, Rumi F, Carrara G, Hutchings A, Schmidt WA, Dasgupta B, Caporali R, Montecucco C, Luqmani R. The impact of disease extent and severity detected by quantitative ultrasound analysis in the diagnosis and outcome of giant cell arteritis. Rheumatology (Oxford). 2020 Sep 1;59(9):2299-2307. doi: 10.1093/rheumatology/kez554. (IF: 5.606; Citations: 3)

Eduardo Dourado, Vítor Teixeira. Bywaters Lesions. J Clin Rheumatol. 2020 Sep 16. doi: 10.1097/RHU.0000000000001541. (IF: 2.360; Citations: 6).

Eduardo Dourado, Margarida Ferro, Catarina Sousa Guerreiro, João Eurico Fonseca. Diet as a Modulator of Intestinal Microbiota in Rheumatoid Arthritis. Nutrients. 2020 Nov 14;12(11):3504. doi: 10.3390/nu12113504. (IF: 4.546; Citations: 1).

Michelsen B, Ørnbjerg LM, Kvien TK, Pavelka K, Nissen MJ, Nordström D, Santos MJ, Koca SS, Askling J, Rotar Z, Gudbjornsson B, Codreanu C, Loft AG, Kristianslund EK, Mann HF, Ciurea A, Eklund KK, Vieira-Sousa E, Yazici A, Jacobsson L, Tomšič M, Löve TJ, Ionescu R, van der Horst-Bruinsma IE, Iannone F, Pombo-Suarez M, Jones GT, Hyldstrup LH, Krogh NS, Hetland ML, Østergaard M. Impact of discordance between patient’s and evaluator’s global assessment on treatment outcomes in 14 868 patients with spondyloarthritis. Rheumatology (Oxford). 2020 Jan 20 (FI: 5.606; Citações:0).

Guerra MG, Martins P, Cruz-Machado AR, Barreira SC, Vieira-Sousa E, Vitorino E, Romeu JC, Khmelinskii N. The Importance of Timely Diagnosing Tuberculous Arthritis: The Role of Ultrasound-Guided Biopsy. J Clin Rheumatol. 2020 Feb 22 doi: 10.1097/RHU.0000000000001346. Epub ahead of print (FI: 2.360; Citações:0)

Marona J, Sepriano A, Rodrigues-Manica S, Pimentel-Santos F, Mourão AF, Gouveia N, Branco JC, Santos H, Vieira-Sousa E, Vinagre F, Tavares-Costa J, Rovisco J, Bernardes M, Madeira N, Cruz-Machado R, Roque R, Silva JL, Marques ML, Ferreira RM, Ramiro S. Eligibility criteria for biologic disease-modifying antirheumatic drugs in axial spondyloarthritis: going beyond BASDAI. RMD Open. 2020 Jan;6(1). (FI:3.44; Citações:1)

Vieira-Sousa E, Alves P, Rodrigues AM, Teixeira F, Tavares-Costa J, Bernardo A, Pimenta S, Pimentel-Santos FM, Gomes JL, Aguiar R, Pinto P, Videira T, Catita C, Santos H, Borges J, Sequeira G, Ribeiro C, Teixeira L, Ávila-Ribeiro P, Martins FM, Canhão H, McInnes IB, Ribeiro RM, Fonseca JE. GO-DACT: a phase 3b randomised, double-blind, placebo-controlled trial of GOlimumab plus methotrexate (MTX) versus placebo plus MTX in improving DACTylitis in MTX-naive patients with psoriatic arthritis. Ann Rheum Dis. 2020 Apr;79(4):490-498. (FI:16.102; Citações:3)

Rodrigues-Manica S, Silva J, Cruz-Machado R, Coelho C, Duarte J, Vieira-Sousa E, Tavares-Costa J, Pimentel-Santos FM. Biologic disease-modifying anti-rheumatic drugs and patient-reported outcomes in axial SpA: a systematic review and a call for action. Clin Rheumatol. 2020 Jun 12. (FI: 2.394; Citações:1)

Vieira-Sousa E Acta Reumatológica Portuguesa 2014-2020: 6 years at a glance.Acta Reumatol Port. 2020 Apr-Jun;45(2):87-88. (FI: 1.183; Citações:0)

Manica SR, Sepriano A, Pimentel-Santos F, Gouveia N, Barcelos A, Branco JC, Bernardes M, Ferreira RM, Vieira-Sousa E, Barreira S, Vinagre F, Roque R, Santos H, Madeira N, Rovisco J, Daniel A, Ramiro S. Effectiveness of switching between TNF inhibitors in patients with axial spondyloarthritis: is the reason to switch relevant? Arthritis Res Ther. 2020 Aug 21;22(1):195. doi: 10.1186/s13075-020-02288-8. (FI: 4.103; Citações:0).

Cruz-Machado AR, Rodrigues-Manica S, Silva JL, Alho I, Coelho C, Duarte J, Florêncio C, Pimentel-Santos FM, Tavares-Costa J, Vieira-Sousa E. Effect of biologic disease-modifying anti-rheumatic drugs targeting remission in axial spondyloarthritis: systematic review and meta-analysis. Rheumatology (Oxford). 2020 Jul 22:keaa268. doi: 10.1093/rheumatology/keaa268. Online ahead of print.PMID: 32696064 Rheumatology (Oxford). 2020 Nov 1;59(11):3158-3171. (FI: 5.606; Citações:0).

Rui Plácido, Tatiana Guimarães, David Jenkins, Paula Campos, Nuno Cortez-Dias, Ana Mineiro, Nuno Lousada, Susana R. Martins, Susana Moreira, Sara Couto Pereira, Catarina Lopes Resende, Rita Vieira, Fausto J. Pinto. Chronic thromboembolic pulmonary hypertension: initial experience of patients undergoing pulmonary thromboendarterectomy. Revista Portuguesa de Cardiologia. Accepted Dec 2020. (FI: 0.96; Citações:1).

Barreira SC, Martins P, Cordeiro I, Fonseca JE, Macieira C. Integrated care process for systemic lupus erythematosus: towards quality in healthcare. Acta Reumatol Port. 2020 Oct-Dec;45(4):295-297. (FI: 1.183; Citações: 0).

Valido A, Dinis JS, Saavedra MJ, Fonseca JE. Tuberculosis under anti-TNF therapy: case series of a center (reporting the experience from the period 2006-2019). Acta Reumatol Port. 2020 Oct-Dec;45(4):281-287. (FI: 1.183; Citações: 0).

Ganhão S, Lucas R, Fonseca JE, Santos MJ, Gonçalves DR, Madeira N, Silva C, Dourado E, Freitas R, Rodrigues J, Azevedo S, Rocha TM, Ferreira RM, Garcia S, Fernandes BM, Prata AR, Couto M, Torres RP, Cunha I, Costa L, Bernardes M. Remission and low disease activity matrix tools: results in real-world rheumatoid arthritis patients under anti-TNF therapy. Acta Reumatol Port. 2020 Oct-Dec;45(4):245-252. (FI: 1.183; Citações: 0).

Belo M, T Alves A, Fonseca JE, Reis J. Rheumatoid nodule mimicking Morton´s neuroma: a rare case report. Acta Reumatol Port. 2020 Jul-Sep;45(3):220-222. (FI: 1.183; Citações: 0).

Sousa S, Santos MJ. Juvenile bullous systemic lupus erythematosus – case report. Acta Reumatol Port 2020;45:74-75. (FI: 1.183; Citações: 0).

Laires PA; Carrilho M; Tavares-Costa J; Lucas P; Machado P; Cunha-Miranda L; Pimentel-Santos F; Santos H; Vieira-Sousa E; Santos MJ; Development and Validation of Psoriatic Arthritis Switch Quality Assessment Tool (PASQAL) – an Outcomes Measurement Tool to Assess the Quality of Biologic Switch Decisions in Psoriatic Arthritis. Acta Reumatol Port. 2020;45:46 (FI: 1.183; Citações: 0).

Fernandes BM, Barreira S, Fonseca JE, Cunha M, Santos MJ, Gonçalves N, Fernandes AL, Rodrigues J, Fontes T, Costa L, Bernardes M. Belimumab in the treatment of Portuguese SLE patients: a real-life multicenter study. Acta Reumatol Port. 2020;45:170-76. (FI: 1.183; Citações: 0).

Cruz-Machado AR, Khmelinskii N (2020). Arthritis mutilans as a radiographic feature of systemic sclerosis. Acta Reumatol Port, 45(3):225-226. English. (FI: 1.183; Citações: 0).

Martins P, Barreira SC, Lopes C, Fonseca JE, Resende C. Rituximab treatment in a spondyloarthritis patient with low-grade follicular lymphoma: a case report. Acta Reumatol Port. 2020 Jul-Sep;45(3):227-228. English. PMID: 33139680. (FI: 1.183; Citações: 0).

Janeiro J, Barreira S, Martins P, Ninitas P, Fonseca JE, Campos J, Monteiro JM. Palm-up test and range of motion in flexion and external rotation provide best correlation with disability and perceived pain in patients with shoulder complaints. Acta Reumatol Port. 2020 Apr-Jun;45(2):95-103. English. PMID: 32895351. (FI: 1.183; Citações: 0).

Fernandes BM, Barreira S, Fonseca JE, Cunha M, Santos MJ, Gonçalves N, Fernandes AL, Rodrigues J, Fontes T, Costa L, Bernardes M. Belimumab in the treatment of Portuguese Systemic Lupus Erythematosus patients: a real-life multicenter study. Acta Reumatol Port. 2020 Jul-Sep;45(3):170-176. English. PMID: 33139681. (FI: 1.183; Citações: 0).

Martins P, Barreira SC, Melo AT, Campanilho-Marques R, Costa-Reis P, Fonseca JE, Oliveira-Ramos F “Transition in a Paediatric Rheumatology Unit – experience from a tertiary unit” -.Acta Reumatol Port. 2019 Oct-Dec;44(4):320-321. (FI: 1.183; Citações: 0).

Soraia Azevedo, Francisca Guimarães, Joana Leite Silva, Rita Barros, Susana Capela, Pedro Abreu, Luís Cunha Miranda, Eduardo Dourado, Augusto Faustino, Joana Ferreira, Vera Las, Filipe Martins, Teresa Martins Rocha, Tiago Meirinhos, Maria João Salvador, Daniela Santos-Faria, Marília Soares Rodrigues, Filipa Teixeira, Inês Cunha. The role of opioid analgesics in rheumatic disorders: a consensus from the Portuguese Rheumatology Society. Acta Reumatol Port. Jan-Mar 2020;45(1):7-19. PMID: 32572015. (FI: 1.183; Citações: 0).

Ganhão S; Lucas R; Fonseca JE; Santos MJ; Gonçalves DR; Madeira N; Silva C; Dourado E; Freitas R; Rodrigues J; Azevedo S; Rocha TM; Ferreira RM; Garcia S; Fernandes BM; Prata AR; Couto M; Torres RP; Cunha I; Costa L; Bernardes M. Remission and low disease activity matrix tool: results in real-world RA patients under anti-TNF therapy. Acta Reumatol Port., Vol 45, nº4 2020. (FI: 1.183; Citações: 0).

Luís M, Garcia S, Guimarães F, António M, Fernandes AL, Araújo F, Cunhs R, Couto M, Pinto AS, Silva L, Cruz M, Santos MJ, Silva J, Duarte C (2015). Early retirement attributed to rheumatoid arthritis and its predictors. Acta Reumatol Port. 2020 Jul-Sep;45(3):177-182 (Impact Factor:, Citations:. Source). (FI: 1.183; Citações: 0).

Vieira-Sousa E, Fonseca JE, Santos MJ. How did COVID-19 pandemic changed the Portuguese rheumatology? Acta Reumatol Port. 2020 Jun 8;45(Jan-Mar (1)):5-6. (FI: 1.183; Citações: 0).

Neto A, Figueiredo G, Saraiva F, Falcão S – Musculoskeletal Ultrasound Among Rheumatologists in Portugal: State of Practice and Training. Acta Reumatológica Portuguesa 2020; 45: 152-154. (FI: 1.183; Citações: 0).

Figueiredo J, Serrado M, Khmelinskii N, do Vale S. Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interaction between inhaled fluticasone and ritonavir. BMJ Case Rep. 2020 May 27;13(5):e233712. doi: 10.1136/bcr-2019-233712. (FI: 0.440; Citações: 0).

Atividade Investigacional/Científica